PERIOPERATIVE USE OF BEVACIZUMAB IN VITRECTOMY FOR PROLIFERATIVE DIABETIC RETINOPATHY: A LITERATURE REVIEW

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GHASEMI FALAVARJANI KH.; MODARES MAHDI

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Journal: JOURNAL OF CURRENT OPHTHALMOLOGY Year:2010 | Volume:22 | Issue:2 Page(s): 5-12

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Title

PERIOPERATIVE USE OF BEVACIZUMAB IN VITRECTOMY FOR PROLIFERATIVE DIABETIC RETINOPATHY: A LITERATURE REVIEW

Author(s)

GHASEMI FALAVARJANI KH. | MODARES MAHDI | Issue Writer Certificate

Keywords

ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR

BEVACIZUMAB

AVASTIN

PROLIFERATIVE DIABETIC RETINOPATHY

VITRECTOMY

Abstract

Purpose: To review the effectiveness and safety of perioperative injection of BEVACIZUMAB in VITRECTOMY for PROLIFERATIVE DIABETIC RETINOPATHY (PDR).Methods: A literature search of all English articles from the Medline and Scopus databases was performed. Original articles, case reports and letters were included. Results: Nineteen, 3 and 5 studies reported preoperative, intraoperative and postoperative intravitreal injection of BEVACIZUMAB, respectively. There are good evidences that preoperative injection of BEVACIZUMAB induces the regression of new vessels, facilitates the surgery and may reduce the incidence of postoperative vitreous hemorrhage in selected eyes. Also, it may decrease the vitreous clear up time for postoperative vitreous hemorrhage. However, the risk of development or progression of tractional retinal detachment (TRD) should be considered. Postoperative complications like the neovascular glaucoma and nonclearing vitreous hemorrhage may be properly managed by intraocular BEVACIZUMAB injection.Conclusion: Preoperative intravitreal BEVACIZUMAB (IVB) seems to be effective and relatively safe for surgical facility with variable effects on postoperative hemorrhage. Postoperative intravitreal injection may be effective for the treatment of postoperative complications.

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APA: Copy

GHASEMI FALAVARJANI, KH., & MODARES, MAHDI. (2010). PERIOPERATIVE USE OF BEVACIZUMAB IN VITRECTOMY FOR PROLIFERATIVE DIABETIC RETINOPATHY: A LITERATURE REVIEW. JOURNAL OF CURRENT OPHTHALMOLOGY, 22(2), 5-12. SID. https://sid.ir/paper/557541/en

Vancouver: Copy

GHASEMI FALAVARJANI KH., MODARES MAHDI. PERIOPERATIVE USE OF BEVACIZUMAB IN VITRECTOMY FOR PROLIFERATIVE DIABETIC RETINOPATHY: A LITERATURE REVIEW. JOURNAL OF CURRENT OPHTHALMOLOGY[Internet]. 2010;22(2):5-12. Available from: https://sid.ir/paper/557541/en

IEEE: Copy

KH. GHASEMI FALAVARJANI, and MAHDI MODARES, “PERIOPERATIVE USE OF BEVACIZUMAB IN VITRECTOMY FOR PROLIFERATIVE DIABETIC RETINOPATHY: A LITERATURE REVIEW,” JOURNAL OF CURRENT OPHTHALMOLOGY, vol. 22, no. 2, pp. 5–12, 2010, [Online]. Available: https://sid.ir/paper/557541/en

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