THE EFFECT OF ANGI PARS AS AN HERBAL MEDICINE ON SPERM COUNT AND THE RATIO OF TESTIS WEIGHT TO BODY WEIGHT IN DIABETIC RATS

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TAGHAVI MOHAMMAD MOHSEN; MAHMOUDIAN ALI REZA; POURMASUMI SOHEYLA; JAFARI NAVEH HAMID REZA; ALAVI SEYED HASAN

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Journal: JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES Year:2011 | Volume:24 | Issue:81 Page(s): 68-75

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Title

THE EFFECT OF ANGI PARS AS AN HERBAL MEDICINE ON SPERM COUNT AND THE RATIO OF TESTIS WEIGHT TO BODY WEIGHT IN DIABETIC RATS

Author(s)

Keywords

DIABETES

ANGI PARS

SPERM NUMBER

MORPHOLOGY OF SPERM

Abstract

Background and purpose: ANGI PARS is a new herbal based compound formulation produced recently for treatment of diabetic foot ulcers by improvement in angiogenesis. This hypothesis suggests that perhaps the drug could reduce adverse effects of DIABETES on the testicular function by improving blood supply. The purpose of the present study was to investigate the effects of ANGI PARS consumption on testis through evaluation of sperm count and sperm morphology in chronic diabetic rats.Materials and methods: This experimental study was carried out on 60 male rats weighing 200 -250 g. The animals were randomly divided into 5 groups (Four experiments and one control). DIABETES was induced by S.C. injection of STZ (60mg/kg) at single dose in all experimental groups. After 56 days, animals in control and first diabetic groups received saline, and in other three diabetic groups received ANGI PARS, insulin and ANGI PARS- insulin, respectively, for 14 days (one spermatogenesis period). Finally, 24 hours after the last injection, animals were anesthesized and sperms were collected from caudal epididymis and number and MORPHOLOGY OF SPERMs were assessed. Collected data were analyzed by ANOVA, using SPSS software.Results: The SPERM NUMBER increased significantly in treatment diabetic groups in comparison with non-treatment diabetic group. In the ANGI PARS-insulin treatment diabetic group, the number of sperm was more than other treatment diabetic groups and was approximately close to the control group.Although in the ANGI PARS-insulin treatment diabetic group, the abnormal sperms were less than other diabetic groups, but this was not statistically significant. Sperm morphology was not significantly different in diabetic groups.Conclusion: The results showed that ANGI PARS has positive effects on number of sperms in diabetic animals especially when it is used with insulin.

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APA: Copy

TAGHAVI, MOHAMMAD MOHSEN, MAHMOUDIAN, ALI REZA, POURMASUMI, SOHEYLA, JAFARI NAVEH, HAMID REZA, & ALAVI, SEYED HASAN. (2011). THE EFFECT OF ANGI PARS AS AN HERBAL MEDICINE ON SPERM COUNT AND THE RATIO OF TESTIS WEIGHT TO BODY WEIGHT IN DIABETIC RATS. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 24(81), 68-75. SID. https://sid.ir/paper/564588/en

Vancouver: Copy

TAGHAVI MOHAMMAD MOHSEN, MAHMOUDIAN ALI REZA, POURMASUMI SOHEYLA, JAFARI NAVEH HAMID REZA, ALAVI SEYED HASAN. THE EFFECT OF ANGI PARS AS AN HERBAL MEDICINE ON SPERM COUNT AND THE RATIO OF TESTIS WEIGHT TO BODY WEIGHT IN DIABETIC RATS. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2011;24(81):68-75. Available from: https://sid.ir/paper/564588/en

IEEE: Copy

MOHAMMAD MOHSEN TAGHAVI, ALI REZA MAHMOUDIAN, SOHEYLA POURMASUMI, HAMID REZA JAFARI NAVEH, and SEYED HASAN ALAVI, “THE EFFECT OF ANGI PARS AS AN HERBAL MEDICINE ON SPERM COUNT AND THE RATIO OF TESTIS WEIGHT TO BODY WEIGHT IN DIABETIC RATS,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 24, no. 81, pp. 68–75, 2011, [Online]. Available: https://sid.ir/paper/564588/en

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