TARGET-CONTROLLED INFUSION OF REMIFENTANIL WITH PROPOFOL OR DESFLURANE UNDER BISPECTRAL INDEX GUIDANCE: QUALITY OF ANESTHESIA AND RECOVERY PROFILE

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MAHLI AHMET; COSKUN DEMET; KARACA GOZDE INAN; AKCALI DIDEM T.; KARABIYIK LALE; KARADENIZLI YENER

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Journal: JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS) Year:2011 | Volume:16 | Issue:5 Page(s): 611-620

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Title

TARGET-CONTROLLED INFUSION OF REMIFENTANIL WITH PROPOFOL OR DESFLURANE UNDER BISPECTRAL INDEX GUIDANCE: QUALITY OF ANESTHESIA AND RECOVERY PROFILE

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Keywords

INFUSION PUMPS

REMIFENTANIL

PROPOFOL

DESFLURANE

CONSCIOUSNESS MONITORS

Abstract

BACKGROUND: Our objective was to examine the clinical properties of two anesthetic regimens, PROPOFOL targetcontrolled infusion (TCI), or DESFLURANE using REMIFENTANIL TCI under bispectral index (BIS) guidance during ear, nose, and throat (ENT) procedures.METHODS: Forty consenting patients who scheduled for ENT procedures were prospectively studied and were included in one of the two groups: TCI group or DESFLURANE (DES) group. General anesthesia was induced with 3 ng mL-1 and 4μg mL-1 effect site concentrations (Ce) of REMIFENTANIL and PROPOFOL, respectively, with TCI system. After intubation, while PROPOFOL infusion was continued in the TCI group, it was ceased in the DES group and DESFLURANE with an initial delivered fraction of 6% was administered. The Ce of PROPOFOL infusion and inspired fraction of DESFLURANE was adjusted in order to keep BIS as 50±10.RESULTS: General mean values of mean arterial pressure (MAP) and heart rate (HR) for the TCI group was significantly higher than DES group (89.3 mmHg and 72.4 bpm vs.77.1 mmHg and 69.5 bpm). Early emergence from anesthesia did not significantly differ between the groups. The rate of patients’ Aldrete score (ARS) to reach 10 was found to be 100% at the 15th min in both groups.CONCLUSIONS: Bispectral index guided combinations of REMIFENTANIL TCI either with PROPOFOL TCI or DESFLURANE anesthetic regimens are both suitable for patients undergoing ENT surgery. The lower blood pressure in the REMIFENTANIL TCI with DESFLURANE anesthetic regimens may be a significant advantage.

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APA: Copy

MAHLI, AHMET, COSKUN, DEMET, KARACA, GOZDE INAN, AKCALI, DIDEM T., KARABIYIK, LALE, & KARADENIZLI, YENER. (2011). TARGET-CONTROLLED INFUSION OF REMIFENTANIL WITH PROPOFOL OR DESFLURANE UNDER BISPECTRAL INDEX GUIDANCE: QUALITY OF ANESTHESIA AND RECOVERY PROFILE. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 16(5), 611-620. SID. https://sid.ir/paper/566833/en

Vancouver: Copy

MAHLI AHMET, COSKUN DEMET, KARACA GOZDE INAN, AKCALI DIDEM T., KARABIYIK LALE, KARADENIZLI YENER. TARGET-CONTROLLED INFUSION OF REMIFENTANIL WITH PROPOFOL OR DESFLURANE UNDER BISPECTRAL INDEX GUIDANCE: QUALITY OF ANESTHESIA AND RECOVERY PROFILE. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2011;16(5):611-620. Available from: https://sid.ir/paper/566833/en

IEEE: Copy

AHMET MAHLI, DEMET COSKUN, GOZDE INAN KARACA, DIDEM T. AKCALI, LALE KARABIYIK, and YENER KARADENIZLI, “TARGET-CONTROLLED INFUSION OF REMIFENTANIL WITH PROPOFOL OR DESFLURANE UNDER BISPECTRAL INDEX GUIDANCE: QUALITY OF ANESTHESIA AND RECOVERY PROFILE,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 16, no. 5, pp. 611–620, 2011, [Online]. Available: https://sid.ir/paper/566833/en

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