مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

286
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

121
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

IMMUNE RESPONSES OF CD4+ T-CELLS OF MDR-TB PATIENTS TO M. TUBERCULOSIS TOTAL LIPID ANTIGENS

Pages

  59-65

Abstract

 Background: CO/T -cell have a central role in protective immune responses to Mycobacterium tuberculosis (M. TUBERCULOSIS) protein antigens, but function of these cells in response to M. TUBERCULOSIS total lipid antigens has remained unclear. The present study was undertaken to detennine role of CO4+ T cells in the MDR-TB patients against M. TUBERCULOSIS total lipid antigens. Materials and Methods: CD4+ T-cells were isolated from MDR-TB patients and stimulated with M. TUBERCULOSIS total lipid antigens. Proliferative responses and cytokine secretion were assessed by MTT and EL/SA, respectively.Results: Our study results showed that proliferative responses of stimulated CO4+T-cells to M. TUBERCULOSIS total lipid antigens and IFN-Y production in MDR-TB patients were significantly lower than those of the PPD-positive subjects (P<0.05) whereas, IL-4 production in the MDR-TB patients was elevated (P<0.05).Conclusion: Responses of CO4+ T -cells of MDR-TB patients to total lipid antigens was significantly lower than that of PPD positive healthy subjects. Therefore, it seems that M. TUBERCULOSIS lipid antigens, as protein antigens, have an important role in specific immune response.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    SHAMSI SHAHOMABADI, A., ZAVARAN HOSSEINI, A., RAYANI, M., VALI ELAHPOUR AMIRI, M., & MASJEDI, M.R.. (2007). IMMUNE RESPONSES OF CD4+ T-CELLS OF MDR-TB PATIENTS TO M. TUBERCULOSIS TOTAL LIPID ANTIGENS. TANAFFOS, 6(1 (21)), 59-65. SID. https://sid.ir/paper/567739/en

    Vancouver: Copy

    SHAMSI SHAHOMABADI A., ZAVARAN HOSSEINI A., RAYANI M., VALI ELAHPOUR AMIRI M., MASJEDI M.R.. IMMUNE RESPONSES OF CD4+ T-CELLS OF MDR-TB PATIENTS TO M. TUBERCULOSIS TOTAL LIPID ANTIGENS. TANAFFOS[Internet]. 2007;6(1 (21)):59-65. Available from: https://sid.ir/paper/567739/en

    IEEE: Copy

    A. SHAMSI SHAHOMABADI, A. ZAVARAN HOSSEINI, M. RAYANI, M. VALI ELAHPOUR AMIRI, and M.R. MASJEDI, “IMMUNE RESPONSES OF CD4+ T-CELLS OF MDR-TB PATIENTS TO M. TUBERCULOSIS TOTAL LIPID ANTIGENS,” TANAFFOS, vol. 6, no. 1 (21), pp. 59–65, 2007, [Online]. Available: https://sid.ir/paper/567739/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button