TUBERCULIN REACTIVITY IN SCHOOL AGE CHILDREN; FIVE-YEAR FOLLOW-UP IN IRAN

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HEMMATI MITRA; GHADIRI KEYGHOBAD; REZAEI MANSOUR

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

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Journal: Iranian Journal of Pediatrics Year:2011 | Volume:21 | Issue:1 Page(s): 39-44

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Information Journal Paper

Title

TUBERCULIN REACTIVITY IN SCHOOL AGE CHILDREN; FIVE-YEAR FOLLOW-UP IN IRAN

Author(s)

HEMMATI MITRA | GHADIRI KEYGHOBAD | REZAEI MANSOUR | Issue Writer Certificate

Keywords

TUBERCULIN SKIN TEST

BCG

VACCINE

PPD

TUBERCULOSIS

Abstract

Objective: TUBERCULOSIS (TB) is an important infectious disease worldwide. TUBERCULIN SKIN TEST (TST) is the standard test for diagnosis of TUBERCULOSIS infection; Bacillus Calmette-Guerin (BCG) vaccination at birth has effects on this test. The aim of this study was to determine the prevalence of positive TST cases among 7- to 11-year-old primary school children and also to follow testpositive individuals for a five-year period.Methods: TST was performed on 10.184 children aged 7-11 years sampled by cluster random method in Kermanshah, West Iran. Those who had a positive test result (i.e. an induration of³15 mm following 72 hours of injecting 0.1 ml of 5 tuberculin units of purified protein derivative from Mycobacterium TUBERCULOSIS) were followed for five years to determine the presence of active TB. Also tuberculin positive rates at cut-off points of 10 mm and ≥15 mm for boys and girls and at different ages were derived and compared using the chi-squared test.Findings: Of 10.184 studied subjects, 830 (8.15%) cases showed positive TST. This rate was 8.7% in boys and 7.8% in girls (P=0.1). A significant linear trend was found between the tuberculin positive rates and age at all cut-off points (P<0.001). No active TB was detected during 5-year follow-up.Conclusion: The rate of positive TST cases in primary school children in Kermanshah, Iran was 8.15% with no new cases of active TUBERCULOSIS detection within five-year follow-up.

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APA: Copy

HEMMATI, MITRA, GHADIRI, KEYGHOBAD, & REZAEI, MANSOUR. (2011). TUBERCULIN REACTIVITY IN SCHOOL AGE CHILDREN; FIVE-YEAR FOLLOW-UP IN IRAN. IRANIAN JOURNAL OF PEDIATRICS, 21(1), 39-44. SID. https://sid.ir/paper/567809/en

Vancouver: Copy

HEMMATI MITRA, GHADIRI KEYGHOBAD, REZAEI MANSOUR. TUBERCULIN REACTIVITY IN SCHOOL AGE CHILDREN; FIVE-YEAR FOLLOW-UP IN IRAN. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2011;21(1):39-44. Available from: https://sid.ir/paper/567809/en

IEEE: Copy

MITRA HEMMATI, KEYGHOBAD GHADIRI, and MANSOUR REZAEI, “TUBERCULIN REACTIVITY IN SCHOOL AGE CHILDREN; FIVE-YEAR FOLLOW-UP IN IRAN,” IRANIAN JOURNAL OF PEDIATRICS, vol. 21, no. 1, pp. 39–44, 2011, [Online]. Available: https://sid.ir/paper/567809/en

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