مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Cites:

1

Information Journal Paper

Title

DETECTING COMMON CFTR MUTATIONS BY REVERSE DOT BLOT HYBRIDIZATION METHOD IN CYSTIC FIBROSIS FIRST REPORT FROM NORTHERN IRAN

Pages

  51-57

Abstract

 Objective: CYSTIC FIBROSIS and its distribution vary widely in different countries and/or ethnic groups. Common CYSTIC FIBROSIS transmembrane conductance regulator (CFTR) mutations were reported from IRAN, but the northern population was not or underrepresented in those studies. The aim of this study was to determine the frequency of commonCFTR/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank"> CFTR mutations in CHILDREN from northern IRAN.Methods: Thirty unrelated IRANian CYSTIC FIBROSIS patients aged less than 11 years and living in Mazandaran province (in IRAN) were screened for 5 commonCFTR/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank"> CFTR gene mutations. DELTAF508, N1303K, G542X, R347H and W1282X using Reverse Dot Blot method.Findings: Only one mutation, DELTAF508, was found in 7 patients accounting for 21.7% (13/60) of alleles.Conclusion: These findings can be used for planning future screening and appropriate genetic counseling programs in IRANian CF families.

Cites

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  • Cite

    APA: Copy

    ESMAEILI DOOKI, MOHAMMAD REZA, AKHAVAN NIAKI, HALEH, & GHABELI JUIBARY, ALI. (2011). DETECTING COMMON CFTR MUTATIONS BY REVERSE DOT BLOT HYBRIDIZATION METHOD IN CYSTIC FIBROSIS FIRST REPORT FROM NORTHERN IRAN. IRANIAN JOURNAL OF PEDIATRICS, 21(1), 51-57. SID. https://sid.ir/paper/573421/en

    Vancouver: Copy

    ESMAEILI DOOKI MOHAMMAD REZA, AKHAVAN NIAKI HALEH, GHABELI JUIBARY ALI. DETECTING COMMON CFTR MUTATIONS BY REVERSE DOT BLOT HYBRIDIZATION METHOD IN CYSTIC FIBROSIS FIRST REPORT FROM NORTHERN IRAN. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2011;21(1):51-57. Available from: https://sid.ir/paper/573421/en

    IEEE: Copy

    MOHAMMAD REZA ESMAEILI DOOKI, HALEH AKHAVAN NIAKI, and ALI GHABELI JUIBARY, “DETECTING COMMON CFTR MUTATIONS BY REVERSE DOT BLOT HYBRIDIZATION METHOD IN CYSTIC FIBROSIS FIRST REPORT FROM NORTHERN IRAN,” IRANIAN JOURNAL OF PEDIATRICS, vol. 21, no. 1, pp. 51–57, 2011, [Online]. Available: https://sid.ir/paper/573421/en

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