CURRENT CHLAMYDIA TRACHOMATIS INFECTION, A MAJOR CAUSE OF INFERTILITY

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MANIA PRAMANIK JAYANTI; KERKAR SHILPA; SONAWANE SHOBHA; MEHTA PRATIBHA; SALVI VINITA

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Journal: Journal of Reproduction & Infertility Year:2012 | Volume:13 | Issue:4 (53) Page(s): 204-210

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Title

CURRENT CHLAMYDIA TRACHOMATIS INFECTION, A MAJOR CAUSE OF INFERTILITY

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Keywords

ASYMPTOMATIC

CHLAMYDIA INFECTION

CURRENT

INFERTILITY

Abstract

Background: In India, the impact of CURRENT Chlamydia trachomatis (C. trachomatis) in reproductive health remains a neglected area of investigation. The present study evaluates if CURRENT CHLAMYDIA INFECTION is associated with any clinical complication that needs the attention of clinical investigators.Methods: In this cross-sectional study, we enrolled 896 women attending the Gynecology Out Patient for the detection of C. trachomatis infection. Polymerase chain reaction was used to diagnose CURRENT C. trachomatis infection and ELISA for past infections. Bacterial vaginosis, Candida and Trichomonas were screened. The results of symptomatic and ASYMPTOMATIC groups were compared. The data was analyzed using E pi Info version 6 and "Z" test. A probability value of p£0.05 was considered as significant.Results: Statistical analysis revealed significant association between CURRENT C. trachomatis infection with INFERTILITY when comparing infected fertile (18.6%vs.9.4%, odds ratio: 2.19, p<0.0005) and uninfected infertile women (45.6%vs.27.3%, odds ratio: 2.24, p<0.0001). Average infection rate was 12.1%, highest in women with INFERTILITY (18.6%) or with ectopic pregnancy (25%). Significant proportions of infected women with INFERTILITY (p<0.01) or with recent pregnancy (p<0.001) were ASYMPTOMATIC.Follow up of infected women who became negative after treatment [28 women from INFERTILITY group and 9 women with recurrent spontaneous abortion (RSA)] revealed live birth in 8 (21.6%) women within one year, 4 with INFERTILITY and 4 with RSA.Conclusion: Study findings suggest association between CURRENT C. trachomatis infection and INFERTILITY. Absence of signs and symptoms associated with this infection highlights its diagnosis in women with a history of INFERTILITY and RSA for their better management, as revealed by live births with one year of follow up.

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APA: Copy

MANIA PRAMANIK, JAYANTI, KERKAR, SHILPA, SONAWANE, SHOBHA, MEHTA, PRATIBHA, & SALVI, VINITA. (2012). CURRENT CHLAMYDIA TRACHOMATIS INFECTION, A MAJOR CAUSE OF INFERTILITY. JOURNAL OF REPRODUCTION AND INFERTILITY, 13(4 (53)), 204-210. SID. https://sid.ir/paper/573570/en

Vancouver: Copy

MANIA PRAMANIK JAYANTI, KERKAR SHILPA, SONAWANE SHOBHA, MEHTA PRATIBHA, SALVI VINITA. CURRENT CHLAMYDIA TRACHOMATIS INFECTION, A MAJOR CAUSE OF INFERTILITY. JOURNAL OF REPRODUCTION AND INFERTILITY[Internet]. 2012;13(4 (53)):204-210. Available from: https://sid.ir/paper/573570/en

IEEE: Copy

JAYANTI MANIA PRAMANIK, SHILPA KERKAR, SHOBHA SONAWANE, PRATIBHA MEHTA, and VINITA SALVI, “CURRENT CHLAMYDIA TRACHOMATIS INFECTION, A MAJOR CAUSE OF INFERTILITY,” JOURNAL OF REPRODUCTION AND INFERTILITY, vol. 13, no. 4 (53), pp. 204–210, 2012, [Online]. Available: https://sid.ir/paper/573570/en

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