THE EFFECT OF OMEGA-3 ON THE SERUM VISFATIN CONCENTRATION IN PATIENTS WITH TYPE II DIABETES

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HAJIANFAR HOSSEIN; HOSSEINZADEH MOHAMMAD JAVAD; BAHONAR AHMAD; MOHAMMAD KAZEM; ASKARI GOLAM REZA; ENTEZARIF MOHAMMAD HASSAN; KESHAVARZ ALI; ANSARI NAZLI

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Journal: JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS) Year:2011 | Volume:16 | Issue:4 Page(s): 490-495

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Title

THE EFFECT OF OMEGA-3 ON THE SERUM VISFATIN CONCENTRATION IN PATIENTS WITH TYPE II DIABETES

Author(s)

Keywords

FATTY ACIDS

OMEGA-3

NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE

DIABETES MELLITUS

TYPE 2

Abstract

BACKGROUND: Visfatin is an adipocytokine which is secreted from adipose tissue and can affect on the diabetes inflammatory reaction and also serum lipids level. On the other hand, OMEGA-3 can also prevent formation of insulin resistance.In the present study, the effect of OMEGA-3 on the serum visfatin concentration was evaluated.METHODS: 71 women with type II diabetes were randomly assigned to the group that took OMEGA-3 capsules or control group with placebo capsules. In the first step, study subjects filled a questionnaire collecting their age, height, weight, waist circumference, and hip circumference. Also their blood samples were taken for blood tests. In the second step, the intervention was done for 8 weeks and in the third step the aforementioned were collected again. In the blood samples visfatin and lipid profiles (low density lipoprotein [LDL], high density lipoprotein [HDL], triglyceride [TG], and cholesterol), glucose and HbA1c were measured.RESULTS: There was no significant difference in serum visfatin level between OMEGA-3 and placebo groups before the intervention (p=0.14), while after the intervention, the mean serum visfatin level in the OMEGA-3 group was significantly higher (p<0.001). In addition, the mean difference between the serum visfatin level before and after the intervention in both groups was significant (p<0.001).CONCLUSIONS: This study showed an increase in visfatin level following consuming OMEGA-3 fats but according to controversial issues on insulin-like function of visfatin, the effects of OMEGA-3 on diabetes should be studied more in further studies.

Cites

EFFECTS OF DIETARY CONJUGATED LINOLEIC ACID ON SERUM VISFATIN LEVEL AND TUMOR NUMBER AND SIZE IN RAT MODEL OF COLORECTAL CANCER

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APA: Copy

HAJIANFAR, HOSSEIN, HOSSEINZADEH, MOHAMMAD JAVAD, BAHONAR, AHMAD, MOHAMMAD, KAZEM, ASKARI, GOLAM REZA, ENTEZARIF, MOHAMMAD HASSAN, KESHAVARZ, ALI, & ANSARI, NAZLI. (2011). THE EFFECT OF OMEGA-3 ON THE SERUM VISFATIN CONCENTRATION IN PATIENTS WITH TYPE II DIABETES. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 16(4), 490-495. SID. https://sid.ir/paper/575908/en

Vancouver: Copy

HAJIANFAR HOSSEIN, HOSSEINZADEH MOHAMMAD JAVAD, BAHONAR AHMAD, MOHAMMAD KAZEM, ASKARI GOLAM REZA, ENTEZARIF MOHAMMAD HASSAN, KESHAVARZ ALI, ANSARI NAZLI. THE EFFECT OF OMEGA-3 ON THE SERUM VISFATIN CONCENTRATION IN PATIENTS WITH TYPE II DIABETES. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2011;16(4):490-495. Available from: https://sid.ir/paper/575908/en

IEEE: Copy

HOSSEIN HAJIANFAR, MOHAMMAD JAVAD HOSSEINZADEH, AHMAD BAHONAR, KAZEM MOHAMMAD, GOLAM REZA ASKARI, MOHAMMAD HASSAN ENTEZARIF, ALI KESHAVARZ, and NAZLI ANSARI, “THE EFFECT OF OMEGA-3 ON THE SERUM VISFATIN CONCENTRATION IN PATIENTS WITH TYPE II DIABETES,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 16, no. 4, pp. 490–495, 2011, [Online]. Available: https://sid.ir/paper/575908/en

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