A FAST AND PRECISE ALGORITHM FOR SIMULTANEOUS ATTENUATION CORRECTION AND RESOLUTION RECOVERY IN BRAIN SPECT: A SIMULATION STUDY

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KALANTARI FARAZ; RAJABI HOSSEIN; RAJABI MOHSEN; EMAMI ALIREZA

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Journal: Iranian Journal of Nuclear Medicine Year:2010 | Volume:18 | Issue:SUPPLEMENT 1 Page(s): 78-78

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Title

A FAST AND PRECISE ALGORITHM FOR SIMULTANEOUS ATTENUATION CORRECTION AND RESOLUTION RECOVERY IN BRAIN SPECT: A SIMULATION STUDY

Author(s)

KALANTARI FARAZ | RAJABI HOSSEIN | RAJABI MOHSEN | EMAMI ALIREZA

Keywords

SPECT

ATTENUATION

RESOLUTION

BRAIN SIMULATION

Abstract

Introduction: The goal of SPECT is determining activity distribution inside the patient body. To achieve this goal a rotating gamma camera acquires many projections around the patient. These projections are later used by reconstruction algorithms to reconstruct the slices corresponding to activity bio distribution. The primary assumption of these algorithms is that Radon transform is a suitable model for image formation. Therefore Filtered Back Projection (FBP) which used inverse Radon transform is the main method for reconstruction; however this model doesn’t consider the effect of ATTENUATION and non-ideal collimation. Therefore the final reconstructed slices degrade due to the effect of photons ATTENUATION and are blurred due to collimator and detector response (CDR) which is the main cause of RESOLUTION degradation. In this study a more suitable model contains the effect of both ATTENUATION and CDR is introduced and used during reconstruction by iterative OSEM algorithm to correct for their degrading effects.Methods: at first a point source of Tc-99m is modeled and placed in different distances from the face of collimator. SIMIND Monte Carlo simulator is used to create projections from this activity source. After finding suitable models, a digital brain phantom (ZUBAL) with a typical Tc99m-ECD distribution is used to validate the ability of our algorithm. The effect of ATTENUATION and CDR were modeled in both projection/backprojection of the OSEM algorithm.Results: qualitatively, better match between activity phantom and reconstructed images are found in comparison with conventional reconstruction algorithms. Quantitatively, a dramatic increase in amount of activity in different parts of brain image is found. The contrast of gray to white matter is increased more than 30%. SNR is also increased by factor of 2. The FWHM of final reconstructed image of point source of activity is also reduced from 7mm at center of field of view to less than 4mm by suggested algorithm which shows a considerable improvement in image RESOLUTION.Conclusion: by using more suitable models for image formation it is possible to reconstruct images with much higher quantitative and qualitative accuracy which is essential in both diagnostic and image guided therapy procedures.

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APA: Copy

KALANTARI, FARAZ, RAJABI, HOSSEIN, RAJABI, MOHSEN, & EMAMI, ALIREZA. (2010). A FAST AND PRECISE ALGORITHM FOR SIMULTANEOUS ATTENUATION CORRECTION AND RESOLUTION RECOVERY IN BRAIN SPECT: A SIMULATION STUDY. IRANIAN JOURNAL OF NUCLEAR MEDICINE, 18(SUPPLEMENT 1), 78-78. SID. https://sid.ir/paper/577484/en

Vancouver: Copy

KALANTARI FARAZ, RAJABI HOSSEIN, RAJABI MOHSEN, EMAMI ALIREZA. A FAST AND PRECISE ALGORITHM FOR SIMULTANEOUS ATTENUATION CORRECTION AND RESOLUTION RECOVERY IN BRAIN SPECT: A SIMULATION STUDY. IRANIAN JOURNAL OF NUCLEAR MEDICINE[Internet]. 2010;18(SUPPLEMENT 1):78-78. Available from: https://sid.ir/paper/577484/en

IEEE: Copy

FARAZ KALANTARI, HOSSEIN RAJABI, MOHSEN RAJABI, and ALIREZA EMAMI, “A FAST AND PRECISE ALGORITHM FOR SIMULTANEOUS ATTENUATION CORRECTION AND RESOLUTION RECOVERY IN BRAIN SPECT: A SIMULATION STUDY,” IRANIAN JOURNAL OF NUCLEAR MEDICINE, vol. 18, no. SUPPLEMENT 1, pp. 78–78, 2010, [Online]. Available: https://sid.ir/paper/577484/en

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