EFFECTS OF HEPARIN LOCK-ANTIBIOTICS TO PREVENT INFECTIONS IN PATIENTS UNDERGOING HEMODIALYSIS: A CLINICAL TRIAL

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SHIRZAD MAHBOOBEH; ESPAHBODI FATEMEH; TAZIKI OMOLBANIN; KHALILIAN ALI REZA

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Journal Paper

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Journal: Journal of Mazandaran University of Medical Sciences Year:2012 | Volume:22 | Issue:96 Page(s): 0-0

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Title

EFFECTS OF HEPARIN LOCK-ANTIBIOTICS TO PREVENT INFECTIONS IN PATIENTS UNDERGOING HEMODIALYSIS: A CLINICAL TRIAL

Author(s)

SHIRZAD MAHBOOBEH | ESPAHBODI FATEMEH | TAZIKI OMOLBANIN | KHALILIAN ALI REZA | Issue Writer Certificate

Keywords

ANTIBIOTIC-HEPARIN LOCK

INFECTION

HEMODIALYSIS

Abstract

Background and purpose: One of the most common complications of catheter in HEMODIALYSIS patients is INFECTIONs and many methods have been proposed to prevent it. This study compared the effects of heparin lock-antibiotics and heparin to prevent INFECTIONs in patients undergoing HEMODIALYSIS.Materials and methods: This single blind clinical trial included 122 patients who were randomly assigned to receive heparin lock (group A) or heparin-antibiotic lock (group B). The subjects in each group were matched for the presence or absence of risk factors. Occurrence of any of the four symptoms of fever, chills (if no other obvious source of INFECTION was found), redness, purulent discharge was considered catheter-site INFECTION. The medication regimens were cefazolin (5 mg/dl) and heparin 2500 IU/ml.Results: The mean age of patients in Group A and B were 57.12±17.34 and 57.61±19.64 years, respectively (P=0.088). The patients who developed INFECTIONs included 22 (36%) patients in group A and 11 (18%) patients in group B (P=0.02).Conclusion: Heparin-cefazolin lock in group B considerably decreased the incidence of catheter INFECTION. Therefore, it could be used as an effective method to prophylaxis of HEMODIALYSIS catheter INFECTION.

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APA: Copy

SHIRZAD, MAHBOOBEH, ESPAHBODI, FATEMEH, TAZIKI, OMOLBANIN, & KHALILIAN, ALI REZA. (2012). EFFECTS OF HEPARIN LOCK-ANTIBIOTICS TO PREVENT INFECTIONS IN PATIENTS UNDERGOING HEMODIALYSIS: A CLINICAL TRIAL. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 22(96), 0-0. SID. https://sid.ir/paper/581894/en

Vancouver: Copy

SHIRZAD MAHBOOBEH, ESPAHBODI FATEMEH, TAZIKI OMOLBANIN, KHALILIAN ALI REZA. EFFECTS OF HEPARIN LOCK-ANTIBIOTICS TO PREVENT INFECTIONS IN PATIENTS UNDERGOING HEMODIALYSIS: A CLINICAL TRIAL. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2012;22(96):0-0. Available from: https://sid.ir/paper/581894/en

IEEE: Copy

MAHBOOBEH SHIRZAD, FATEMEH ESPAHBODI, OMOLBANIN TAZIKI, and ALI REZA KHALILIAN, “EFFECTS OF HEPARIN LOCK-ANTIBIOTICS TO PREVENT INFECTIONS IN PATIENTS UNDERGOING HEMODIALYSIS: A CLINICAL TRIAL,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 22, no. 96, pp. 0–0, 2012, [Online]. Available: https://sid.ir/paper/581894/en

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