ASSESSMENT OF ORAL ACETAZOLAMIDE ON POSTOPERATIVE PAIN AFTER LAPAROSCOPIC CHOLECYSTECTOMY

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MOAZENI BISTGANI M.; MOHAMMAD ALI BEYGI F.; SHAHRJERDI SHAHNAZ

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Paper Information

Journal: Journal of Shahrekord University of Medical Sciences Year:2010 | Volume:12 | Issue:2 Page(s): 21-26

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Title

ASSESSMENT OF ORAL ACETAZOLAMIDE ON POSTOPERATIVE PAIN AFTER LAPAROSCOPIC CHOLECYSTECTOMY

Author(s)

MOAZENI BISTGANI M. | MOHAMMAD ALI BEYGI F. | SHAHRJERDI SHAHNAZ | Issue Writer Certificate

Keywords

ACETAZOLAMIDEQ3

LAPAROSCOPYQ3

TISSUE ACIDOSISQ2

POSTOPERATIVE PAINQ3

Abstract

Background and aim: Carbon dioxide (Co2) is used during LAPAROSCOPY for producing pneumoperttoneum. Combination of this gas with irrigation fluid in the abdomen produces carbonic acid which creates two kinds of abdominal and referred pain to right shoulder. In the present research, we have studied the effect of oral ACETAZOLAMIDE in reducing POSTOPERATIVE PAIN after laparoscopic cholecystectomy.Methods: This clinical trial was performed in 88 patients with cholelithiasis without any complication that were candidate for laparoscopic cholecystectomy. The patients devided randomly and equally mg 250 (The experimental group received ACETAZOLAMIDE. in two groups and control group received) hours 8 every, hours before surgery24, orallyplacebo. Abdominal and shoulder pain measured using McGill pain score by a person who was blind for both groups. Pain measurement was performed in four different times, before and after the surgery, discharge from recovery and 24 hours after surgery. Data were analyzed by using SPSS software.Results: We observed that mean pain scores was significantly higher in ACETAZOLAMIDE group compared to the placebo group, 24 hours after the operation (P<0.05). However; no significant changes were observed between groups in other times (P>0.05).Conclusion: Although ACETAZOLAMIDE can reduce abdominal pain referred to right shoulder by reducing acidity in peritoneal irrigation fluid, but this drug can increase abdominal pain in the site of surgery with damaged tissues by producing TISSUE ACIDOSIS (as a side effect of drug).

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APA: Copy

MOAZENI BISTGANI, M., MOHAMMAD ALI BEYGI, F., & SHAHRJERDI, SHAHNAZ. (2010). ASSESSMENT OF ORAL ACETAZOLAMIDE ON POSTOPERATIVE PAIN AFTER LAPAROSCOPIC CHOLECYSTECTOMY. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 12(2), 21-26. SID. https://sid.ir/paper/58312/en

Vancouver: Copy

MOAZENI BISTGANI M., MOHAMMAD ALI BEYGI F., SHAHRJERDI SHAHNAZ. ASSESSMENT OF ORAL ACETAZOLAMIDE ON POSTOPERATIVE PAIN AFTER LAPAROSCOPIC CHOLECYSTECTOMY. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2010;12(2):21-26. Available from: https://sid.ir/paper/58312/en

IEEE: Copy

M. MOAZENI BISTGANI, F. MOHAMMAD ALI BEYGI, and SHAHNAZ SHAHRJERDI, “ASSESSMENT OF ORAL ACETAZOLAMIDE ON POSTOPERATIVE PAIN AFTER LAPAROSCOPIC CHOLECYSTECTOMY,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 12, no. 2, pp. 21–26, 2010, [Online]. Available: https://sid.ir/paper/58312/en

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