ANTI NOCICEPTIVE AND ANTI-INFLAMMATORY EFFECTS OF AERIAL PARTS OF GUNDELIA TOURNEFORTII L. ON NMRI MALE MICE

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ORYAN SH.; NASRI S.; AMIN GH.R.; KAZEMI MOHAMMADI S.M.M.

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Journal: Journal of Shahrekord University of Medical Sciences Year:2011 | Volume:12 | Issue:4 (SUPPL 1) Page(s): 8-15

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Title

ANTI NOCICEPTIVE AND ANTI-INFLAMMATORY EFFECTS OF AERIAL PARTS OF GUNDELIA TOURNEFORTII L. ON NMRI MALE MICE

Author(s)

ORYAN SH. | NASRI S. | AMIN GH.R. | KAZEMI MOHAMMADI S.M.M. | Issue Writer Certificate

Keywords

ANTINOCICEPTIVEQ3

ANTI-INFLAMMATORYQ3

EXTRACTQ2

GUNDELIA TOURNEFORTII LQ3

NMRI MALE MICEQ3

Abstract

Background and aim: Gundelia tournefortii is traditionally used to relieve pain and inflammation. The aim of this study was to evaluate the ANTINOCICEPTIVE and anti- inflammatory effects of Gundelia tournefortii in mice.Methods: After determining the Lethal Dose (LD50) of the total EXTRACT of Gundelia tournefortii, its different doses of total EXTRACT was injected in mice (IP) and then ANTINOCICEPTIVE and ANTI-INFLAMMATORY effects were determined by formalin and xylene tests.Results: The result of this study demonstrated that the total EXTRACT of Gundelia tournefortii in doses of 0.3, 0.6, 1.2 and 2.4 g/kg induced significant ANTINOCICEPTIVE and ANTI-INFLAMMATORY effects compared to the control group. The most effective dose of EXTRACT was found at 2.4 g/kg. LD50 was obtained at 6.28 g/kg of animal weight.Conclusions: The total EXTRACT of Gundelia tournefortii significantly reduces the nociception and inflammation.

Cites

ANTI-INFLAMMATORY AND ANTI-NOCICEPTIVE EFFECTS OF EXTRACT CONTAINS AND WITHOUT GLYCYRRHIZIC ACID OF GLYCYRRHIZA GLABRA RHIZOME IN MALE MICE

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APA: Copy

ORYAN, SH., NASRI, S., AMIN, GH.R., & KAZEMI MOHAMMADI, S.M.M.. (2011). ANTI NOCICEPTIVE AND ANTI-INFLAMMATORY EFFECTS OF AERIAL PARTS OF GUNDELIA TOURNEFORTII L. ON NMRI MALE MICE. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 12(4 (SUPPL 1)), 8-15. SID. https://sid.ir/paper/58491/en

Vancouver: Copy

ORYAN SH., NASRI S., AMIN GH.R., KAZEMI MOHAMMADI S.M.M.. ANTI NOCICEPTIVE AND ANTI-INFLAMMATORY EFFECTS OF AERIAL PARTS OF GUNDELIA TOURNEFORTII L. ON NMRI MALE MICE. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2011;12(4 (SUPPL 1)):8-15. Available from: https://sid.ir/paper/58491/en

IEEE: Copy

SH. ORYAN, S. NASRI, GH.R. AMIN, and S.M.M. KAZEMI MOHAMMADI, “ANTI NOCICEPTIVE AND ANTI-INFLAMMATORY EFFECTS OF AERIAL PARTS OF GUNDELIA TOURNEFORTII L. ON NMRI MALE MICE,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 12, no. 4 (SUPPL 1), pp. 8–15, 2011, [Online]. Available: https://sid.ir/paper/58491/en

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