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Information Journal Paper

Title

ANTIBIOTIC RESISTANCE AND DISTRIBUTION OF BETA-LACTAMASE RESISTANCE GENES IN ESCHERICHIA COLI STRAINS ISOLATED FROM URINARY TRACT INFECTION IN WOMEN AND CHILDREN IN FARSAN TOWN

Pages

  53-61

Abstract

 Background and aims: Urinary tract infection is one of the most common infections in women and children and Escherichia coli is considered as the main cause of infection. RESISTANCE against antibiotics is an important problem used in the treatment. This study was aimed to determine the prevalence of antibiotic RESISTANCE and RESISTANCE genes to antibiotics.Methods: A cross-sectional study of 120 cases of women and children with urinary tract infection was performed in 2013 in the clinics of Farsan. Samples of bacteria were grown on Blood Agar and Eosin Methylene Blue Agar (EMB), and then by using antibiogram Kirby-bauer method and the zone of growth inhibition were examined. The Polymerase Chain Reaction (PCR) was used to determine the prevalence of RESISTANCE genes CTX, CTX-M, TEM and B-SHV, respectively.Results: Of 120 samples under study, 95 (79%) of cases were identified E.COLI. The results of antimicrobial RESISTANCE test, the highest RESISTANCE to ampicillin (95.78%), trimethoprim- sulfamethoxazole (62.10%), nitrofurantoin (42.10%) and the most sensitive to ciprofloxacin (46.31%) and ceftriaxone (44.21%) were reported, respectively. Moreover, the PCR results showed CTX was the highest and SHV-B was the lowest prevalence between RESISTANCE genes.Conclusion: The results showed the prevalence of E.COLI producing beta-lactamase RESISTANCE genes are on the rise. It is also better to use less than ampicillin, trimethoprim- sulfamethoxazole and nitrofurantoin in the primary treatment of URINARY TRACT INFECTIONS.

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    APA: Copy

    DOOSTI, A., DARUOSHI, M., BORZA, R., & PASAND, M.. (2016). ANTIBIOTIC RESISTANCE AND DISTRIBUTION OF BETA-LACTAMASE RESISTANCE GENES IN ESCHERICHIA COLI STRAINS ISOLATED FROM URINARY TRACT INFECTION IN WOMEN AND CHILDREN IN FARSAN TOWN. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 17(6), 53-61. SID. https://sid.ir/paper/58684/en

    Vancouver: Copy

    DOOSTI A., DARUOSHI M., BORZA R., PASAND M.. ANTIBIOTIC RESISTANCE AND DISTRIBUTION OF BETA-LACTAMASE RESISTANCE GENES IN ESCHERICHIA COLI STRAINS ISOLATED FROM URINARY TRACT INFECTION IN WOMEN AND CHILDREN IN FARSAN TOWN. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2016;17(6):53-61. Available from: https://sid.ir/paper/58684/en

    IEEE: Copy

    A. DOOSTI, M. DARUOSHI, R. BORZA, and M. PASAND, “ANTIBIOTIC RESISTANCE AND DISTRIBUTION OF BETA-LACTAMASE RESISTANCE GENES IN ESCHERICHIA COLI STRAINS ISOLATED FROM URINARY TRACT INFECTION IN WOMEN AND CHILDREN IN FARSAN TOWN,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 17, no. 6, pp. 53–61, 2016, [Online]. Available: https://sid.ir/paper/58684/en

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