DETECTION OF CH50 AND ROLE OF C3, C4 COMPLEMENT IN PATIENTS WITH CANDIDIASIS

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MOGHIM H.; GHAVARNI-NEJAD A.

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Journal: Journal of Shahrekord University of Medical Sciences Year:2000 | Volume:2 | Issue:1 Page(s): 61-65

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Information Journal Paper

Title

DETECTION OF CH50 AND ROLE OF C3, C4 COMPLEMENT IN PATIENTS WITH CANDIDIASIS

Author(s)

MOGHIM H. | GHAVARNI-NEJAD A. | Issue Writer Certificate

Keywords

CANDIDIASISQ3

COMPLEMENTQ4

LEUKEMIAQ3

LYMPHOMAQ3

Abstract

CANDIDIASIS is a type of opportunistic fungal disease with some predisposing factors such as hematologic disorders (e.g. LEUKEMIA, LYMPHOMA). Since the COMPLEMENT system plays a major role in its prevention, we investigated and compared the role of C3, C4 and the rate of hemolytic activity of CH5O in two groups: Case group consisted of patients having LEUKEMIA and LYMPHOMA as well as CANDIDIASIS. Control group consisted of patients having leukernia and LYMPHOMA but not CANDIDIASIS. The method of sensitization of sheep blood by embosebtor was employed to assess the rate of activity of the COMPLEMENT, and the mean of C3 and C4 was measured by immunodiffusion method. T-test was used for comparison of the two groups. There was a significant decrease in the mean of C3 COMPLEMENT and CH50 in the case group compared to those of the control group (p<0.05). But there was no significant difference in the mean of C4 between two groups. Therefore a decrease of C3 and CH50 may play a role in producing CANDIDIASIS along with LEUKEMIA and LYMPHOMA.

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APA: Copy

MOGHIM, H., & GHAVARNI-NEJAD, A.. (2000). DETECTION OF CH50 AND ROLE OF C3, C4 COMPLEMENT IN PATIENTS WITH CANDIDIASIS. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 2(1), 61-65. SID. https://sid.ir/paper/58863/en

Vancouver: Copy

MOGHIM H., GHAVARNI-NEJAD A.. DETECTION OF CH50 AND ROLE OF C3, C4 COMPLEMENT IN PATIENTS WITH CANDIDIASIS. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2000;2(1):61-65. Available from: https://sid.ir/paper/58863/en

IEEE: Copy

H. MOGHIM, and A. GHAVARNI-NEJAD, “DETECTION OF CH50 AND ROLE OF C3, C4 COMPLEMENT IN PATIENTS WITH CANDIDIASIS,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 2, no. 1, pp. 61–65, 2000, [Online]. Available: https://sid.ir/paper/58863/en

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