THE EFFECT OF CHRONIC EXPOSURE TO LOW LEVEL LEAD ON LEARNING AND MEMORY DURING TWO DIFFERENT DEVELOPMENTAL PHASES OF RAT

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

HOUSHMAND F.; ALAEI H.; FESHARAKI MEHRAFARIN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Shahrekord University of Medical Sciences Year:2002 | Volume:4 | Issue:3 Page(s): 27-35

Download Full-Text

Persian Verion

View:

799

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF CHRONIC EXPOSURE TO LOW LEVEL LEAD ON LEARNING AND MEMORY DURING TWO DIFFERENT DEVELOPMENTAL PHASES OF RAT

Author(s)

HOUSHMAND F. | ALAEI H. | FESHARAKI MEHRAFARIN | Issue Writer Certificate

Keywords

LEAD ACETATEQ2

ACTIVE AVOIDANCE LEARNINGQ4

MEMORYQ2

RATQ3

Abstract

Low-level lead exposure during brain development is known to affect functions of the central nervous system. The behavioral effects of lead have been studied extensively. Despite these efforts, the results are controversial so that the same behavioral test often produced conflicting results in different investigations. This study was carried out to assess the effects of exposure to chronic low level lead during two different phases of development: breast feeding (I) and after weaning (II) on learning and MEMORY by active avoidance method. Wistar RATs were exposed to the metal during breast feeding (I) and after weaning (II) for 21 days, by replacing the drinking water of experimental groups by 0.05, 0.1, 0.2% LEAD ACETATE solution. Each test group had a corresponding control group receiving twice distilled water. Compared to the control groups, in phase I, a dose of 0.05% of LEAD ACETATE caused an increase in learning and MEMORY, 0.2% produced an increase in MEMORY and 0.1 % caused a decrease in MEMORY. In phase II doses of 0.05% and 0.2% of LEAD ACETATE caused an increase in learning and MEMORY. These data indicate that in chronic low-level lead poisoning, learning and MEMORY are influenced by both the doses of the lead and the developmental phase. Different effects of lead exposure in children and adults, as well as inconsistencies between in vivo and in vitro studies, suggest that lead toxicity may have multiple mechanisms in the central nervous system.

Cites

No record.

References

No record.

Cite

APA: Copy

HOUSHMAND, F., ALAEI, H., & FESHARAKI, MEHRAFARIN. (2002). THE EFFECT OF CHRONIC EXPOSURE TO LOW LEVEL LEAD ON LEARNING AND MEMORY DURING TWO DIFFERENT DEVELOPMENTAL PHASES OF RAT . JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 4(3), 27-35. SID. https://sid.ir/paper/58964/en

Vancouver: Copy

HOUSHMAND F., ALAEI H., FESHARAKI MEHRAFARIN. THE EFFECT OF CHRONIC EXPOSURE TO LOW LEVEL LEAD ON LEARNING AND MEMORY DURING TWO DIFFERENT DEVELOPMENTAL PHASES OF RAT . JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2002;4(3):27-35. Available from: https://sid.ir/paper/58964/en

IEEE: Copy

F. HOUSHMAND, H. ALAEI, and MEHRAFARIN FESHARAKI, “THE EFFECT OF CHRONIC EXPOSURE TO LOW LEVEL LEAD ON LEARNING AND MEMORY DURING TWO DIFFERENT DEVELOPMENTAL PHASES OF RAT ,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 4, no. 3, pp. 27–35, 2002, [Online]. Available: https://sid.ir/paper/58964/en

Related Journal Papers