THE EFFECT OF INTERFERENCE OF MORPHINE AND IMMOBILITY STRESS ON PERFORMANCE OF PITUITARY–ADRENAL AXIS IN MATURE MALE RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

HOSSEINI S.E.; HEIDARI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Hormozgan Medical Journal Year:2014 | Volume:18 | Issue:1 Page(s): 11-20

Download Full-Text

Persian Verion

View:

838

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF INTERFERENCE OF MORPHINE AND IMMOBILITY STRESS ON PERFORMANCE OF PITUITARY–ADRENAL AXIS IN MATURE MALE RATS

Author(s)

HOSSEINI S.E. | HEIDARI M. | Issue Writer Certificate

Keywords

ACTHQ3

CORTICOSTERONEQ2

MORPHINEQ2

RATSQ2

Abstract

Introduction: MORPHINE is an alkaloid from the poppy plant (papaver somniferum) is extracted and used by millions of people around the world and also types of stresses threated such as immobility stress the health of many people. The aim of this study was to investigate the interference of MORPHINE and immobility stress on plasma levels of hormones of ACTH and CORTICOSTERONE in mature male RATS.Methods: In this empirical study, 70 mature male Wistar RATS were enrolled as the control, sham and experiment groups, randomly. 3 experimental groups of different types received doses of 10, 20 and 30 mg/kgBW MORPHINE, and 2 experimental group, one received for 2 hours immobility stress and other for 2 hours immobility stress and other plus MORPHINE with doses of 30 mg/kgBW and the sham group received 1cc of saline intraperitoneally for 5 days. 24 hours after the last injection, mice were bled from the heart and hormones of ACTH and CORTICOSTERONE levels were measured. The data were evaluated using ANOVA and Tuky test.Results: The results showed that the maximum dose of MORPHINE and immobility stress increases plasma levels of ACTH and CORTICOSTERONE hormones (P<0.001) and simultaneous administration of MORPHINE and immobilization stress enhances the effect of each alone.Conclusion: MORPHINE and immobility stress intensify their effect on hormones of ACTH and CORTICOSTERONE. Therefore, further investigation can discover on the role of stress and MORPHINE on disease incidence and disease prevention, in particular psychosomatic in human specimens.

Cites

No record.

References

No record.

Cite

APA: Copy

HOSSEINI, S.E., & HEIDARI, M.. (2014). THE EFFECT OF INTERFERENCE OF MORPHINE AND IMMOBILITY STRESS ON PERFORMANCE OF PITUITARY–ADRENAL AXIS IN MATURE MALE RATS. HORMOZGAN MEDICAL JOURNAL, 18(1), 11-20. SID. https://sid.ir/paper/60603/en

Vancouver: Copy

HOSSEINI S.E., HEIDARI M.. THE EFFECT OF INTERFERENCE OF MORPHINE AND IMMOBILITY STRESS ON PERFORMANCE OF PITUITARY–ADRENAL AXIS IN MATURE MALE RATS. HORMOZGAN MEDICAL JOURNAL[Internet]. 2014;18(1):11-20. Available from: https://sid.ir/paper/60603/en

IEEE: Copy

S.E. HOSSEINI, and M. HEIDARI, “THE EFFECT OF INTERFERENCE OF MORPHINE AND IMMOBILITY STRESS ON PERFORMANCE OF PITUITARY–ADRENAL AXIS IN MATURE MALE RATS,” HORMOZGAN MEDICAL JOURNAL, vol. 18, no. 1, pp. 11–20, 2014, [Online]. Available: https://sid.ir/paper/60603/en

Related Journal Papers