PRENATAL SCREENING FOR CHROMOSOMAL ABNORMALITIES IN TABRIZ, NORTH-WEST OF IRAN

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

FARDYAZAR ZAHRA; VAZIFEHKHAH SHABNAM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Zahedan Journal of Research in Medical Sciences Year:2013 | Volume:15 | Issue:9 Page(s): 68-73

Download Full-Text

View:

258

Download:

109

Cites:

Information Journal Paper

Title

PRENATAL SCREENING FOR CHROMOSOMAL ABNORMALITIES IN TABRIZ, NORTH-WEST OF IRAN

Author(s)

FARDYAZAR ZAHRA | VAZIFEHKHAH SHABNAM | Issue Writer Certificate

Keywords

MATERNAL AGE

CHROMOSOMAL ABERRATIONS

NUCHAL TRANSLUCENCY

TRISOMY 21

Abstract

Background: Several studies have indicated that when compared to non-consanguinous marriage, consanguinous marriage may lead to a higher incidence of congenital abnormalities. The study was performed to evaluate few screening tests to estimate the risk of chromosomal abnormalities in the first trimester compared between familial and non-familial marriages.Materials and Methods: In this cross sectional study, 300 pregnant women with singleton pregnancy presenting to Tabriz Al-Zahra hospital from 2007 to 2009 were enrolled as study population. The participants were evaluated about chromosomal malformations using a combination of NT (Nuchal Translucency), PAPP-A (Pregnancy-Associated Plasma Protein A), and free beta- human chorionic gonadotropin (b-hCG). In positive screening test results, the participants underwent fetal karyotyping using amniocentesis or chorionic villi sampling (CVS).Results: Pregnancies with higher risk were observed more among non-consanguineous marriages. The MATERNAL AGE was not found to be a determinant in this regard. NT and free bhCG values (but not PAPP-A) were significantly different between the two study groups. The triple screening test had a sensitivity of 100%. There were two cases of Down syndrome both belonging to the MATERNAL AGE less than 35 years and non-consanguineous marriages.Conclusion: Considering that a statistically significant association was not observed between abnormal test results and pregnancy complications (p=0.73), it seems that it is essential to use screening tests in all pregnant women. Especially that the only two pregnancies with Down syndrome in our study were under 35 years of age.

Cites

No record.

References

No record.

Cite

APA: Copy

FARDYAZAR, ZAHRA, & VAZIFEHKHAH, SHABNAM. (2013). PRENATAL SCREENING FOR CHROMOSOMAL ABNORMALITIES IN TABRIZ, NORTH-WEST OF IRAN. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), 15(9), 68-73. SID. https://sid.ir/paper/607340/en

Vancouver: Copy

FARDYAZAR ZAHRA, VAZIFEHKHAH SHABNAM. PRENATAL SCREENING FOR CHROMOSOMAL ABNORMALITIES IN TABRIZ, NORTH-WEST OF IRAN. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH)[Internet]. 2013;15(9):68-73. Available from: https://sid.ir/paper/607340/en

IEEE: Copy

ZAHRA FARDYAZAR, and SHABNAM VAZIFEHKHAH, “PRENATAL SCREENING FOR CHROMOSOMAL ABNORMALITIES IN TABRIZ, NORTH-WEST OF IRAN,” ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), vol. 15, no. 9, pp. 68–73, 2013, [Online]. Available: https://sid.ir/paper/607340/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops