مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Cites:

1

Information Journal Paper

Title

ALOE VERA LEAF GEL IN TREATMENT OF ADVANCED TYPE 2 DIABETES MELLITUS NEEDING INSULIN THERAPY: A RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED CLINICAL TRIAL

Pages

  19-27

Abstract

 Background: Advanced TYPE 2 DIABETES mellitus (T2DM) needing insulin therapy is a common disease. Previous studies indicate that aloe (ALOE VERA L.) leaf gel may positively affect the blood glucose and lipid levels in PATIENTs with advanced T2DM needing insulin.Objective: Evaluation of the efficacy and safety of aloe leaf gel in the treatment of type 2 diabetic PATIENTs resistant to oral synthetic anti-hyperglycemic drugs needing insulin.Methods: In this randomized double - blind placebo-controlled clinical trial with the PATIENTs aged 40-60 years, the efficacy and safety of taking aloe leaf gel (one 300 mg capsule every 12 hours for 2 months) combined with oral synthetic anti-hyperglycemic drugs in treatment of 35 PATIENTs were evaluated and compared with the placebo group (n = 35).Results: The aloe leaf gel lowered the blood levels of fasting glucose and glycosylated hemoglobin significantly (p = 0.041 and p = 0.023 respectively) without any significant effects on the lipid profile and liver/kidney function tests (p > 0.05) compared with placebo at the endpoint. No adverse effects were reported.Conclusion: The results suggest that aloe leaf gel may safely improve GLYCEMIC CONTROL in PATIENTs with advanced T2DM needing insulin.

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    APA: Copy

    FALLAH HUSEINI, H., KIANBAKHT, S., HAJIAGHAEE, R., AFKHAMI ARDEKANI, M., BONAKDARAN, A., & HASHEM DABAGHIAN, F.. (2012). ALOE VERA LEAF GEL IN TREATMENT OF ADVANCED TYPE 2 DIABETES MELLITUS NEEDING INSULIN THERAPY: A RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED CLINICAL TRIAL. JOURNAL OF MEDICINAL PLANTS, 11(43), 19-27. SID. https://sid.ir/paper/608574/en

    Vancouver: Copy

    FALLAH HUSEINI H., KIANBAKHT S., HAJIAGHAEE R., AFKHAMI ARDEKANI M., BONAKDARAN A., HASHEM DABAGHIAN F.. ALOE VERA LEAF GEL IN TREATMENT OF ADVANCED TYPE 2 DIABETES MELLITUS NEEDING INSULIN THERAPY: A RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED CLINICAL TRIAL. JOURNAL OF MEDICINAL PLANTS[Internet]. 2012;11(43):19-27. Available from: https://sid.ir/paper/608574/en

    IEEE: Copy

    H. FALLAH HUSEINI, S. KIANBAKHT, R. HAJIAGHAEE, M. AFKHAMI ARDEKANI, A. BONAKDARAN, and F. HASHEM DABAGHIAN, “ALOE VERA LEAF GEL IN TREATMENT OF ADVANCED TYPE 2 DIABETES MELLITUS NEEDING INSULIN THERAPY: A RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED CLINICAL TRIAL,” JOURNAL OF MEDICINAL PLANTS, vol. 11, no. 43, pp. 19–27, 2012, [Online]. Available: https://sid.ir/paper/608574/en

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