THE EFFECT OF INTRAVENOUS CEFAZOLIN ON INFECTIOUS COMPLICATIONS FOLLOWING LOW- RISK CESAREAN

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HADAVAND SH.; TORKESTANI F.; ZAFARGHANDI N.; ZAYERI F.; VAZIRI MARYAM

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Journal: Journal of Advances in Medical and Biomedical Research Year:2008 | Volume:15 | Issue:61 Page(s): 29-37

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Title

THE EFFECT OF INTRAVENOUS CEFAZOLIN ON INFECTIOUS COMPLICATIONS FOLLOWING LOW- RISK CESAREAN

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Keywords

CESAREANQ2

INFECTIOUS COMPLICATIONSQ3

PROPHYLACTIC ANTIBIOTICQ3

Abstract

Background and objective: CESAREAN section is one of the most common surgeries in modern obstetrics.Infectious complications such as fever, wound infection, endometritis and urinary tract infection are the most serious complications following CESAREAN. Nevertheless, there are no uniform recommendations regarding the application of PROPHYLACTIC ANTIBIOTICs. Since inappropriate application of antibiotics could impose high costs as well as drug side effects and emergence of resistant microorganisms, this study was carried out with the aim of evaluating the effect of PROPHYLACTIC ANTIBIOTICs on INFECTIOUS COMPLICATIONS following the low-risk CESAREAN section.Materials and Methods: This prospective, clinical trial study was performed on 257 patients who underwent low-risk CESAREAN section. The patients were randomly divided into treatment (A) and control (B) groups.The patients in group A received 2gr intravenous cefazolin at cord clamping, while the control group received no antibiotic. The patients were evaluated during the first 48 hours, the first week, the second week, and the sixth week following the surgery and INFECTIOUS COMPLICATIONS were compared in two groups.Results: Out of 257 patients, 16 cases (6.2%) developed INFECTIOUS COMPLICATIONS of whom 6 patients (4.7%) were in group A and 10 patients (7.8%) fell into group B. Complications included fever (2.3% in each group), endometritis (0.8% in group A and 2.3% in group B), urinary infection (1.6% in group A and 3.1% in group B), wound infection (1.6% in group A and 2.3% in group B) and wound dehiscence (1.6% in each group). No significant difference was observed between the administration of PROPHYLACTIC ANTIBIOTIC and the complications. Moreover, the duration of hospital stay following CESAREAN section was not statistically different in each group.Conclusion: Based on the study findings it can be recommended that PROPHYLACTIC ANTIBIOTIC be restricted only to the high-risk CESAREAN section individuals.

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APA: Copy

HADAVAND, SH., TORKESTANI, F., ZAFARGHANDI, N., ZAYERI, F., & VAZIRI, MARYAM. (2008). THE EFFECT OF INTRAVENOUS CEFAZOLIN ON INFECTIOUS COMPLICATIONS FOLLOWING LOW- RISK CESAREAN. JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH, 15(61), 29-37. SID. https://sid.ir/paper/61036/en

Vancouver: Copy

HADAVAND SH., TORKESTANI F., ZAFARGHANDI N., ZAYERI F., VAZIRI MARYAM. THE EFFECT OF INTRAVENOUS CEFAZOLIN ON INFECTIOUS COMPLICATIONS FOLLOWING LOW- RISK CESAREAN. JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH[Internet]. 2008;15(61):29-37. Available from: https://sid.ir/paper/61036/en

IEEE: Copy

SH. HADAVAND, F. TORKESTANI, N. ZAFARGHANDI, F. ZAYERI, and MARYAM VAZIRI, “THE EFFECT OF INTRAVENOUS CEFAZOLIN ON INFECTIOUS COMPLICATIONS FOLLOWING LOW- RISK CESAREAN,” JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH, vol. 15, no. 61, pp. 29–37, 2008, [Online]. Available: https://sid.ir/paper/61036/en

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