PRETREATMENT WITH OLIVE LEAF EXTRACT ON LIVER INJURY FOLLOWING ISCHEMIA-REPERFUSION IN MALE RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

NASIRZADEH M.R.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Advances in Medical and Biomedical Research Year:2016 | Volume:24 | Issue:103 Page(s): 71-80

Download Full-Text

Persian Verion

View:

896

Download:

Cites:

Information Journal Paper

Title

PRETREATMENT WITH OLIVE LEAF EXTRACT ON LIVER INJURY FOLLOWING ISCHEMIA-REPERFUSION IN MALE RATS

Author(s)

NASIRZADEH M.R. | Issue Writer Certificate

Keywords

RENAL ISCHEMIC-REPERFUSION INJURYQ1

OLIVE LEAF EXTRACTQ2

LIVER ANTIOXIDANT ENZYMEQ1

MALE RATQ2

Abstract

Background and Objective: Wheras RENAL ISCHEMIC-REPERFUSION INJURY increases lipid peroxidation level in the liver tissues, it decreases the antioxidant activity and antioxidant enzymes. Olive leaves are considered as significant sources of bioactive phenolic compounds with superior antioxidant capacity, anti-inflammatory and radical scavenging.Materials and Methods: In this study 50 MALE RATs were allocated randomly to 5 groups: 1) control, 2) 1h I/R, 3) 1h I/R-OLE (Olive Leaf Extract), 4) 24h I/R and 5) 24hI/R-OLE. The animals received 100 mg/kg OLIVE LEAF EXTRACT in 0.5 ml drinking water using gavage for 28 days in 3and 5 groups before induction of ischemia (1hour). Other animals received 0.5 ml normal saline by gavages. At the end of the reperfusion period (1and 24 hours respectively), the serum level of urea, creatinine and liver enzymes as well as antioxidant enzymes including MDA, SOD and GPX were determined in liver tissue.Results: MDA level in OLE- treated groups decreased significantly compared to ischemic-reperfusion groups (p<0.05). In the meantime, it was detected that activity level of SOD and GPX in liver tissue of ischemic groups was significantly lower in comparison to OLE treated groups (p<0.05).Conclusion: This study enlightened that OLE is a protective agent against RENAL ISCHEMIC-REPERFUSION INJURY in liver tissue.

Cites

STUDY OF ANTIOXIDANT STATUS AND OXIDATIVE STRESS IN DIABETIC RATS TREATED WITH ROYAL JELLY

References

No record.

Cite

APA: Copy

NASIRZADEH, M.R.. (2016). PRETREATMENT WITH OLIVE LEAF EXTRACT ON LIVER INJURY FOLLOWING ISCHEMIA-REPERFUSION IN MALE RATS. JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH, 24(103), 71-80. SID. https://sid.ir/paper/61296/en

Vancouver: Copy

NASIRZADEH M.R.. PRETREATMENT WITH OLIVE LEAF EXTRACT ON LIVER INJURY FOLLOWING ISCHEMIA-REPERFUSION IN MALE RATS. JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH[Internet]. 2016;24(103):71-80. Available from: https://sid.ir/paper/61296/en

IEEE: Copy

M.R. NASIRZADEH, “PRETREATMENT WITH OLIVE LEAF EXTRACT ON LIVER INJURY FOLLOWING ISCHEMIA-REPERFUSION IN MALE RATS,” JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH, vol. 24, no. 103, pp. 71–80, 2016, [Online]. Available: https://sid.ir/paper/61296/en

Related Journal Papers