EFFECT OF VITAMIN E SUPPLEMENTATION ON METABOLIC STATUS AND SERUM LIPOPROTEIN (A) LEVEL IN TYPE 2

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RAFRAF M.; BAZYUN B.; SARABCHIAN M.A.; SAFAEIYAN A.

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Journal: Journal of Advances in Medical and Biomedical Research Year:2014 | Volume:22 | Issue:91 Page(s): 84-94

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Title

EFFECT OF VITAMIN E SUPPLEMENTATION ON METABOLIC STATUS AND SERUM LIPOPROTEIN (A) LEVEL IN TYPE 2

Author(s)

RAFRAF M. | BAZYUN B. | SARABCHIAN M.A. | SAFAEIYAN A. | Issue Writer Certificate

Keywords

VITAMIN EQ2

METABLIC STATUSQ2

LIPOPROTEIN (A)Q3

TYPE 2 DIABETESQ2

Abstract

Background and Objective: TYPE 2 DIABETES represents an independent risk factor for cardiovascular diseases. The aim of the present study was to investigate the effects of VITAMIN E supplementation on metabolic status and serum lipoprotein (a) level in type 2 diabetic patients.Materials and Methods: In this randomized double-blind, controlled clinical trial 83 type 2 diabetic patients (men and woman) were assigned into two groups as the intervention and control groups. The intervention group (n=42) took 400 IU VITAMIN E per day and the control group (n=41) received placebo for 8 weeks.Anthropometric measurements, dietary intake data and fasting blood samples were obtained from each patient before and after the end of study.Results: Serum VITAMIN E and lipid-standardized a-tocopherol significantly increased after VITAMIN E supplementation in the intervention group (P=0.0001). A significant decrease in fasting blood glucose was observed in the VITAMIN E group compared with the placebo group at the end of the study (P=0.027).Alterations in body mass index, dietary intakes, levels of lipoprotein (a) and other serum lipids were not significant in any of the groups.Conclusion: VITAMIN E supplementation led to an improvement in the status of serum VITAMIN E and glycemic control in type 2 diabetic patients. VITAMIN E as pertained to the dose and duration throughout this study did not produce any significant difference in other variables. Further studies are suggested to evaluate the possible outcomes of VITAMIN E on metabolic control in type 2 diabetic patients.

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APA: Copy

RAFRAF, M., BAZYUN, B., SARABCHIAN, M.A., & SAFAEIYAN, A.. (2014). EFFECT OF VITAMIN E SUPPLEMENTATION ON METABOLIC STATUS AND SERUM LIPOPROTEIN (A) LEVEL IN TYPE 2. JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH, 22(91), 84-94. SID. https://sid.ir/paper/61630/en

Vancouver: Copy

RAFRAF M., BAZYUN B., SARABCHIAN M.A., SAFAEIYAN A.. EFFECT OF VITAMIN E SUPPLEMENTATION ON METABOLIC STATUS AND SERUM LIPOPROTEIN (A) LEVEL IN TYPE 2. JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH[Internet]. 2014;22(91):84-94. Available from: https://sid.ir/paper/61630/en

IEEE: Copy

M. RAFRAF, B. BAZYUN, M.A. SARABCHIAN, and A. SAFAEIYAN, “EFFECT OF VITAMIN E SUPPLEMENTATION ON METABOLIC STATUS AND SERUM LIPOPROTEIN (A) LEVEL IN TYPE 2,” JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH, vol. 22, no. 91, pp. 84–94, 2014, [Online]. Available: https://sid.ir/paper/61630/en

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