ISOLATION OF HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS AND DEVELOPMENT OF AN ANGIOGENESIS MODEL IN FIBRIN MATRIX

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MANSOURI K.; SHEYKH ALESLAMI A.; BAHRAMI GH.R.; MOSTAFAEI ALI

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Advances in Medical and Biomedical Research Year:2006 | Volume:14 | Issue:55 Page(s): 17-22

Download Full-Text

Persian Verion

View:

1,413

Download:

Cites:

Information Journal Paper

Title

ISOLATION OF HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS AND DEVELOPMENT OF AN ANGIOGENESIS MODEL IN FIBRIN MATRIX

Author(s)

MANSOURI K. | SHEYKH ALESLAMI A. | BAHRAMI GH.R. | MOSTAFAEI ALI | Issue Writer Certificate

Keywords

ANGIOGENESISQ2

ENDOTHELIAL CELLQ3

UMBILICAL VEINQ4

Abstract

Background & Objective: ANGIOGENESIS plays a key role in different physiologic and pathologic processes. Evaluation of ENDOTHELIAL CELLs and finally new vessels development in-vivo is a complex and formidable task. Thus, we designed an in-vitro experimental ANGIOGENESIS model using human UMBILICAL VEIN ENDOTHELIAL CELLs (HUVEC) which is highly reproducible and controllable. This model has applicability to study various parameters involved in ANGIOGENESIS and its harness.Materials and Methods: HUVEC cells were isolated from UMBILICAL VEIN by enzyme treatment as the source of ENDOTHELIAL CELLs. Then, the three-dimensional model was designed using fibrin gel and cytodex beads which was covered by HUVEC cells.Results: In this model 10-12 days after culturing HUVEC, the resulting capillary formation was observed as branching of the source ENDOTHELIAL CELLs in microscopic field.Conclusion: The model is controllable and highly reproducible to study various parameters involved in ANGIOGENESIS. Moreover, the model provides a reliable method to screen ANGIOGENESIS and anti-ANGIOGENESIS substances.

Cites

No record.

References

DESIGNING AN EXPERIMENTAL ANGIOGENESIS MODEL IN A THREE DIMENSIONAL MATRIX OF FIBRIN TO EVALUATE NEOPLASTIC GROWTH INHIBITORS

Cite

APA: Copy

MANSOURI, K., SHEYKH ALESLAMI, A., BAHRAMI, GH.R., & MOSTAFAEI, ALI. (2006). ISOLATION OF HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS AND DEVELOPMENT OF AN ANGIOGENESIS MODEL IN FIBRIN MATRIX. JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH, 14(55), 17-22. SID. https://sid.ir/paper/61671/en

Vancouver: Copy

MANSOURI K., SHEYKH ALESLAMI A., BAHRAMI GH.R., MOSTAFAEI ALI. ISOLATION OF HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS AND DEVELOPMENT OF AN ANGIOGENESIS MODEL IN FIBRIN MATRIX. JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH[Internet]. 2006;14(55):17-22. Available from: https://sid.ir/paper/61671/en

IEEE: Copy

K. MANSOURI, A. SHEYKH ALESLAMI, GH.R. BAHRAMI, and ALI MOSTAFAEI, “ISOLATION OF HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS AND DEVELOPMENT OF AN ANGIOGENESIS MODEL IN FIBRIN MATRIX,” JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH, vol. 14, no. 55, pp. 17–22, 2006, [Online]. Available: https://sid.ir/paper/61671/en

Related Journal Papers