THE EFFECTS OF INTRADERMAL BOTULINUM TOXIN TYPE A INJECTIONS ON PAIN SYMPTOMS OF PATIENTS WITH DIABETIC NEUROPATHY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

GHASEMI MAJID; ANSARI MARYAM; BASIRI KEIVAN; SHAIGANNEJAD VAHID

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS) Year:2014 | Volume:18 | Issue:2 Page(s): 106-111

Download Full-Text

View:

361

Download:

169

Cites:

Information Journal Paper

Title

THE EFFECTS OF INTRADERMAL BOTULINUM TOXIN TYPE A INJECTIONS ON PAIN SYMPTOMS OF PATIENTS WITH DIABETIC NEUROPATHY

Author(s)

GHASEMI MAJID | ANSARI MARYAM | BASIRI KEIVAN | SHAIGANNEJAD VAHID | Issue Writer Certificate

Keywords

BOTULINUM TOXIN TYPE A

DIABETIC PERIPHERAL NEUROPATHY

PAIN

Abstract

Background: Considering the dramatic increasing rate of diabetes and consequently its related complications, most importantly DIABETIC PERIPHERAL NEUROPATHY (DPN), challenges regarding proper treatment of DPN and its effect on the quality-of-life and care of diabetic patients, the aim of this current study is to evaluate the effect of intradermal BOTULINUM TOXIN TYPE A (BTX-A) injections on PAIN symptoms of patients with diabetic neuropathic PAIN.Materials and Methods: In this randomized double-blind placebo-controlled clinical trial study, diabetic patients aged<70 years with neuropathic PAIN in both feet were enrolled. Diabetic neuropathy (DN) in selected patients was diagnosed using DN4 questionnaire and nerve conduction velocity examinations. They randomized in two intervention (BTX-A injection/100 unit, N=20) and placebo groups (normal saline injection, N=20). The outcome of injection on diabetic neuropathic PAIN was assessed using neuropathy PAIN scale (NPS) and visual analog scale (VAS) score and compared in two studied groups.Results: There was no significant difference in DN4, NPS and VAS scales of studied population after intervention in the placebo group. Intradermal injection of BTX-A reduced NPS scores for all items except cold sensation (P=0.05). It reduced DN4 scores for electric shocks, burning, pins and needles and brushing (P<0.05). According to VAS scale 30% and 0% of patients in intervention and placebo groups have no PAIN after intervention (P=0.01).Conclusion: Intradermal injection of BTX-A is a well-tolerated agent that has a significant effect on DPN PAIN.

Cites

No record.

References

No record.

Cite

APA: Copy

GHASEMI, MAJID, ANSARI, MARYAM, BASIRI, KEIVAN, & SHAIGANNEJAD, VAHID. (2014). THE EFFECTS OF INTRADERMAL BOTULINUM TOXIN TYPE A INJECTIONS ON PAIN SYMPTOMS OF PATIENTS WITH DIABETIC NEUROPATHY. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 18(2), 106-111. SID. https://sid.ir/paper/622104/en

Vancouver: Copy

GHASEMI MAJID, ANSARI MARYAM, BASIRI KEIVAN, SHAIGANNEJAD VAHID. THE EFFECTS OF INTRADERMAL BOTULINUM TOXIN TYPE A INJECTIONS ON PAIN SYMPTOMS OF PATIENTS WITH DIABETIC NEUROPATHY. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2014;18(2):106-111. Available from: https://sid.ir/paper/622104/en

IEEE: Copy

MAJID GHASEMI, MARYAM ANSARI, KEIVAN BASIRI, and VAHID SHAIGANNEJAD, “THE EFFECTS OF INTRADERMAL BOTULINUM TOXIN TYPE A INJECTIONS ON PAIN SYMPTOMS OF PATIENTS WITH DIABETIC NEUROPATHY,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 18, no. 2, pp. 106–111, 2014, [Online]. Available: https://sid.ir/paper/622104/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops