مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

386
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

272
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

EVALUATION OF IMMUNE RESPONSE AFTER MODERATE AND OVERTRAINING EXERCISE IN WISTAR RAT

Pages

  1-8

Abstract

 Objective(s): The effect of prolonged overtraining on cytokine kinetics was compared with MODERATE EXERCISE in the present study.Materials and Methods: Male Wistar RATs were randomly divided into control sedentary (C), moderate trained (MT), (V=20 m/min, 30 min/day for 6 days a week, 8 weeks), overtrained (OT) (V=25 m/min, 60min/day for 6 days a week, 11 weeks) and recovered overtrained (OR) (OT plus 2 weeks recovery) groups, (n=6 for each group). Immediately, 24 hr and 2 weeks (in OR) after last bout of exercise blood samples were obtained. The plasma concentrations of TNFa, IL-6, IL-10, IL-4 and IFNg were measured by ELISA method.Results: Immediately after last bout of exercise the following findings were observed; IL-6, IL-10 and TNFαconcentrations increased in OT and OR groups compared with control (P<0.05– P<0.001). Serum level of IL-4 decreased (P<0.01) but IFNg increased (P<0.05) in MT group vs. control. In addition, circulatory levels of TNFa IL-6, IL-10 and IL-4 were higher but the IFNg concentrations were lower in OT and OR groups than MT group (P<0.05- P<0.01). The IFN-gIL4 RATio was significantly increased in MT (P<0.01) while it decreased in OT group. There were not statistical differences in TNFa IL-6, and IFNg levels between different time intervals after exercise in MT, OT and OR groups.Conclusion: These data confirm a positive effect of MODERATE EXERCISE on immune function and a decrease in susceptibility to viral infection by inducing TH1 cytokine profile shift. However, prolonged and OVERTRAINING EXERCISE causes numerous changes in immunity that possibly reflects physiological stress and immune suppression.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    GHOLAMNEZHAD, ZAHRA, BOSKABADY, MOHAMMAD HOSSEIN, HOSSEINI, MAHMOUD, SANKIAN, MOJTABA, & KHAJAVI RAD, ABOLFAZL. (2014). EVALUATION OF IMMUNE RESPONSE AFTER MODERATE AND OVERTRAINING EXERCISE IN WISTAR RAT. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 17(1), 1-8. SID. https://sid.ir/paper/630552/en

    Vancouver: Copy

    GHOLAMNEZHAD ZAHRA, BOSKABADY MOHAMMAD HOSSEIN, HOSSEINI MAHMOUD, SANKIAN MOJTABA, KHAJAVI RAD ABOLFAZL. EVALUATION OF IMMUNE RESPONSE AFTER MODERATE AND OVERTRAINING EXERCISE IN WISTAR RAT. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2014;17(1):1-8. Available from: https://sid.ir/paper/630552/en

    IEEE: Copy

    ZAHRA GHOLAMNEZHAD, MOHAMMAD HOSSEIN BOSKABADY, MAHMOUD HOSSEINI, MOJTABA SANKIAN, and ABOLFAZL KHAJAVI RAD, “EVALUATION OF IMMUNE RESPONSE AFTER MODERATE AND OVERTRAINING EXERCISE IN WISTAR RAT,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 17, no. 1, pp. 1–8, 2014, [Online]. Available: https://sid.ir/paper/630552/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button