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Title

EVALUATION OF THE EFFECT OF PROPOFOL AND SODIUM THIOPENTAL ON BLOOD PRESSURE AND HEART RATE DURING INDUCTION IN ELECTIVE SURGERY IN SINA HOSPITAL IN TEHRAN, 1380-1381

Pages

  5-9

Abstract

 Sodium thiopental and PROPOFOL are two populary used anesthetic induction agents that have different pharmacological and pharmacokinetic actions. It is not clear how the HEMODYNAMIC RESPONSES differ in patients using these two drugs for anesthetic induction. The aim of this study was to investigate the HEMODYNAMIC RESPONSES of patients receiving PROPOFOL and thiopental during endotracheal intubation.Sixty male patients, 20 to 50 years old, were included in this study. Patients were randomly divided into two groups according to different inductive anesthetics. Non invasive blood pressure (NIBP) monitoring was performed in five stages, A: Before premedication, B: Before induction with 5 mg/kg thiopental or 2 mg/kg PROPOFOL intravenously, C: Immediately after intubation, D: Five minutes after intubation and E: Five minutes after surgical incision.Propofol induction produced smaller mean arterial pressure and heart rate changes immediately after intubation and five minutes after surgical incision than the thiopental group (1.16% and 9.59% decreases in PROPOFOL group VS. 22.57% and 9.92% increases in the thiopental group immediately after intubation and five minutes after surgical incision, p<0.0005). Differences in heart rate changes between PROPOFOL and thiopental groups were found in patients. (0.42 and 4.81% decreases in PROPOFOL group VS. 39.23% and 20.10% increases in thiopental group immediately after intubation and five minutes after surgical incision. P<0.0005).Propofol induction produced more stable hemodynamics after intubation in patients than did thiopental induction therefore, it is suggested to use PROPOFOL for induction and intubation in patients.

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    APA: Copy

    HASSANI MIANROODI, M., MAHFOUZI, A., & KAZEMI, H.A.. (2002). EVALUATION OF THE EFFECT OF PROPOFOL AND SODIUM THIOPENTAL ON BLOOD PRESSURE AND HEART RATE DURING INDUCTION IN ELECTIVE SURGERY IN SINA HOSPITAL IN TEHRAN, 1380-1381. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 22(38), 5-9. SID. https://sid.ir/paper/63110/en

    Vancouver: Copy

    HASSANI MIANROODI M., MAHFOUZI A., KAZEMI H.A.. EVALUATION OF THE EFFECT OF PROPOFOL AND SODIUM THIOPENTAL ON BLOOD PRESSURE AND HEART RATE DURING INDUCTION IN ELECTIVE SURGERY IN SINA HOSPITAL IN TEHRAN, 1380-1381. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2002;22(38):5-9. Available from: https://sid.ir/paper/63110/en

    IEEE: Copy

    M. HASSANI MIANROODI, A. MAHFOUZI, and H.A. KAZEMI, “EVALUATION OF THE EFFECT OF PROPOFOL AND SODIUM THIOPENTAL ON BLOOD PRESSURE AND HEART RATE DURING INDUCTION IN ELECTIVE SURGERY IN SINA HOSPITAL IN TEHRAN, 1380-1381,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 22, no. 38, pp. 5–9, 2002, [Online]. Available: https://sid.ir/paper/63110/en

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    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
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