ASSESSING ANALGESIC EFFECT OF EXTRAPLEURAL INFUSION OF ROPIVACAINE ON POSTTHORACOTOMY SURGERY IN NEONATES UP TO SEVEN DAYS

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SADEGHI A.; ROUZROKH M.; MIRKHESHTI A.R.; RAZAVI S.J.; KOURANLOU J.; KHALEGHNEZHAD TABARI A.

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Journal: JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE Year:2006 | Volume:28 | Issue:54 Page(s): 20-27

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Title

ASSESSING ANALGESIC EFFECT OF EXTRAPLEURAL INFUSION OF ROPIVACAINE ON POSTTHORACOTOMY SURGERY IN NEONATES UP TO SEVEN DAYS

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Keywords

PAINQ2

NEONATEQ3

EXTRAPLEURALQ3

ROPIVACAINEQ3

Abstract

Background: Insufficient control of post-thoracotomy PAIN can create prolonged stay in NICU and Hospital, increasing incidence and severity of pulmonary complications such as atelectasis, pneumonia or pulmonary failure through compromising natural pulmonary mechanisms. The aim of this study was determining analgesic effect of continuous extra pleural nerve block using ROPIVACAINE after thoracotmy surgery in NEONATEs < 7 days and the incidence of atelectasis and duration of hospitalization in NICU. Materials and methods: 41 NEONATEs < 7 days that were thoracotomy candidate, allocated randomly into two groups in a controlled clinical trial. The cases received extra pleural infusion of ROPIVACAINE (0.1 m/kg hr) for 48 hours and controls who were managed according to routine protocol of "Mofid Children Hospital". Hemodynamically unstable patients and those who suffered from hospital infections were excluded from the study. After the surgery all patients had spontaneous breathing. PAIN level was determined for each NEONATE based on NIPS grading. The incidence of atelectasis in first 48 hours after operation and duration of NICU stay were also determined. Results: There were no significant differences in mean age, sex proportions and mean weight between the two groups. One of cases excluded because of hemodyamic instability. Mean PAIN score in the group received ROPIVACAINE (1.9±0.7) was significantly less than the control group (5.2±0.6) (p<0.0001). Five percent of cases (n=1) but 100% of controls (n=20) had PAIN score equal or greater than 3 (p<0.0001).The incidence of atelactasis among cases was marginally less than controls (35% vs. 65% respectively; p=0.58). Duration of hospitalization in case group (12±5.6 days) has no significant difference from control group (13.6±4.8 days) (p=0.3). Discussion: The results show that continuous EXTRAPLEURAL infusion of ROPIVACAINE reduces the PAIN markedly and atelectasis after thoracotomy surgery in NEONATEs younger than 7 days.

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APA: Copy

SADEGHI, A., ROUZROKH, M., MIRKHESHTI, A.R., RAZAVI, S.J., KOURANLOU, J., & KHALEGHNEZHAD TABARI, A.. (2006). ASSESSING ANALGESIC EFFECT OF EXTRAPLEURAL INFUSION OF ROPIVACAINE ON POSTTHORACOTOMY SURGERY IN NEONATES UP TO SEVEN DAYS. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 28(54), 20-27. SID. https://sid.ir/paper/63269/en

Vancouver: Copy

SADEGHI A., ROUZROKH M., MIRKHESHTI A.R., RAZAVI S.J., KOURANLOU J., KHALEGHNEZHAD TABARI A.. ASSESSING ANALGESIC EFFECT OF EXTRAPLEURAL INFUSION OF ROPIVACAINE ON POSTTHORACOTOMY SURGERY IN NEONATES UP TO SEVEN DAYS. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2006;28(54):20-27. Available from: https://sid.ir/paper/63269/en

IEEE: Copy

A. SADEGHI, M. ROUZROKH, A.R. MIRKHESHTI, S.J. RAZAVI, J. KOURANLOU, and A. KHALEGHNEZHAD TABARI, “ASSESSING ANALGESIC EFFECT OF EXTRAPLEURAL INFUSION OF ROPIVACAINE ON POSTTHORACOTOMY SURGERY IN NEONATES UP TO SEVEN DAYS,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 28, no. 54, pp. 20–27, 2006, [Online]. Available: https://sid.ir/paper/63269/en

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