COMPARISON OF CONTROLLED MECHANICAL VENTILATION PLUS PEEP TO PRESSURE CONTROLLED INVERSE RATIO VENTILATION IN MANAGEMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME

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GHAZI SAEIDI KIOUMARS; ARBABI SH.; AFRASIAB Z.; GOLBABAEE SH.

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Journal: JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE Year:2005 | Volume:27 | Issue:49 Page(s): 12-20

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Title

COMPARISON OF CONTROLLED MECHANICAL VENTILATION PLUS PEEP TO PRESSURE CONTROLLED INVERSE RATIO VENTILATION IN MANAGEMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME

Author(s)

GHAZI SAEIDI KIOUMARS | ARBABI SH. | AFRASIAB Z. | GOLBABAEE SH. | Issue Writer Certificate

Keywords

ARDSQ3

CMV+PEEP. PC-IRVQ4

Abstract

known as a mainstay in respiratory management of ARDS patients. Pressure controlled - inverse ratio (PC-IRV) with I/E=2/1 ventilation is another technique which can be used for respiratory management of these patients. AS there is still controversy in which technique is the best for respiratory management in ARDS patients, this study was done to compare the effect of CMV+PEEP and PC-IRV on pulmonary and hemodynamic parameters in ARDS patients. Materials and Method: In this prospective randomized clinical trial study, 50 ARDS patients requiring mechanical ventilation were divided into two groups. 25 of them underwent mechanical ventilation with CMV+PEEP (group 1) and the other 25 were ventilated with PCV-IRV technique (group 2). Ventilatory parameters (Vt, RR, PEEP, FiO2) and inspiratory flow waveform were kept constant in both groups. Mean arterial blood press Peak Inspiratory Pressure (PIP), Mean Airway Pressure (MAP), Plateau Pessure (Pplat), Peak Inspiratory Pressure (PIP), ABG, and PaO2/FiO2 were measured at first and sixth hours after the start of mechanichal ventilation in both groups and the results were compared to those obtained at hour zero. Results: PaO2 and PaO2/FiO2 were both increased at first and sixth hour of ventilatory support in both groups, and the PaO2/FiO2 obtained at the first and 6th hour was significantly higher in patients on PC-IRV compared to patients on CMV+PEEP. PIP was significantly less in PC-IRV group when compared to CMV + PEEP group at the first and 6th hour of ventilation. Pplat remianed less than 30 cm of water in PC-IRV group. MAP was increased insignificantly at first and 6th hour PC-IRV group. Mean arterial pressure was decreased insignificantly in both groups. Decrease of pulse pressure was significantly less in PC-IRVgroup at hour 6th in comparison to hour zero. Conclusion: In comparison to CMV+PEEP, PC-IRV technique increases oxygenation and decreases PIP in ARDS patients.

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APA: Copy

GHAZI SAEIDI, KIOUMARS, ARBABI, SH., AFRASIAB, Z., & GOLBABAEE, SH.. (2005). COMPARISON OF CONTROLLED MECHANICAL VENTILATION PLUS PEEP TO PRESSURE CONTROLLED INVERSE RATIO VENTILATION IN MANAGEMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 27(49), 12-20. SID. https://sid.ir/paper/63427/en

Vancouver: Copy

GHAZI SAEIDI KIOUMARS, ARBABI SH., AFRASIAB Z., GOLBABAEE SH.. COMPARISON OF CONTROLLED MECHANICAL VENTILATION PLUS PEEP TO PRESSURE CONTROLLED INVERSE RATIO VENTILATION IN MANAGEMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2005;27(49):12-20. Available from: https://sid.ir/paper/63427/en

IEEE: Copy

KIOUMARS GHAZI SAEIDI, SH. ARBABI, Z. AFRASIAB, and SH. GOLBABAEE, “COMPARISON OF CONTROLLED MECHANICAL VENTILATION PLUS PEEP TO PRESSURE CONTROLLED INVERSE RATIO VENTILATION IN MANAGEMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 27, no. 49, pp. 12–20, 2005, [Online]. Available: https://sid.ir/paper/63427/en

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