EVALUATION OF THE EFFECTS INJECTION OF BUPIVACAINE WITH INTRAABDOMINAL METHOD IN RELEASE OF POSTOPERATIVE PAIN AFTER LAPAROSCOPIC CHOLECYSTECTOMY

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NASIRAN B.; RAHBAR N.; JAFARI AMIR MASOUD

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Journal: JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE Year:2006 | Volume:28 | Issue:55 Page(s): 35-43

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Title

EVALUATION OF THE EFFECTS INJECTION OF BUPIVACAINE WITH INTRAABDOMINAL METHOD IN RELEASE OF POSTOPERATIVE PAIN AFTER LAPAROSCOPIC CHOLECYSTECTOMY

Author(s)

NASIRAN B. | RAHBAR N. | JAFARI AMIR MASOUD | Issue Writer Certificate

Keywords

BUPIVACAINEQ3

INTRA – ABDOMINALQ3

LAPAROSCOPIC CHOLECYSTECTOMYQ3

POSTOPERATIVE PAINQ3

Abstract

Background: Intra-operative injection of local anesthetics is going to be more common in daily practice of surgery and POSTOPERATIVE PAIN management. One of the POSTOPERATIVE PAIN management is intra-abdominal injection of local anesthetics. The aim of this study was to evaluate the effects of intraabdominal injection of BUPIVACAINE on POSTOPERATIVE PAIN after LAPAROSCOPIC CHOLECYSTECTOMY. Materials and Method: In a randomized placebo controlled clinical trial, 60 adult patients with cholelithiasis referring to the Amir-al-momenin Hospital requiring cholecystectomy were enrolled. All the patients underwent laparoscopic cholecystectoy under general anesthesia in a unique manner. In the end of surgery the patients were randomly assigned in the control and bupiva- caine groups. In the BUPIVACAINEgroup, intra- abdominal injection 0.8 cc/kg of 0.25% bupivacalne in the gallbladder site was utilized and in control group normal saline injection was utilized. The POSTOPERATIVE PAIN was evaluated by visual analogue scale 0/AS) in recovery, 2, 4 and 6 hours postoperatively, the total dose of opiate consumption in the first 6 hours, heart rate and mean arterial pressure (MAP) were measured. The 0.5 mg/kg of pethidine was administrated via IM root at patient's request each time. Results: The means of VAS were lower in buplvacalne group compared with control group during the first 6 hours (in BUPIVACAINE and control group were respectively in recovery 32.7±23.62 vs. 89.0±10.6, 43.3±20 vs 66.0±9.3 in 2 hours. 26.7±13.5 vs 65.3±9.3 in 4 hours, 17.0±15.8 vs 69.3±9.8 in 6 hours). Also the means of heart rate and MAP In recovery and 6 hours postoperatively were significantly lower In bupivacalne group compared to control group. Furthermore the mean of opiate consumption and the frequency of patients' analgesic request were significantly lower in BUPIVACAINE group compared to control group (2.5±0.5 vs. 10.3±1.8 mg and 50% vs. 100% respectively). Conclusion: It seems that intra-abdominal injection of 0.8 cc/kg of 0.25% buplvacalne in the galbladder site in patients undergoing iaparoscopic cholecystoctomy significantly reduces POSTOPERATIVE PAIN and opiate request and consumption.

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APA: Copy

NASIRAN, B., RAHBAR, N., & JAFARI, AMIR MASOUD. (2006). EVALUATION OF THE EFFECTS INJECTION OF BUPIVACAINE WITH INTRAABDOMINAL METHOD IN RELEASE OF POSTOPERATIVE PAIN AFTER LAPAROSCOPIC CHOLECYSTECTOMY. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 28(55), 35-43. SID. https://sid.ir/paper/63431/en

Vancouver: Copy

NASIRAN B., RAHBAR N., JAFARI AMIR MASOUD. EVALUATION OF THE EFFECTS INJECTION OF BUPIVACAINE WITH INTRAABDOMINAL METHOD IN RELEASE OF POSTOPERATIVE PAIN AFTER LAPAROSCOPIC CHOLECYSTECTOMY. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2006;28(55):35-43. Available from: https://sid.ir/paper/63431/en

IEEE: Copy

B. NASIRAN, N. RAHBAR, and AMIR MASOUD JAFARI, “EVALUATION OF THE EFFECTS INJECTION OF BUPIVACAINE WITH INTRAABDOMINAL METHOD IN RELEASE OF POSTOPERATIVE PAIN AFTER LAPAROSCOPIC CHOLECYSTECTOMY,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 28, no. 55, pp. 35–43, 2006, [Online]. Available: https://sid.ir/paper/63431/en

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