ANALGESIC EFFECTS OF KETAMINE VS. DEXMEDETOMIDINE ON OPIOID ABUSERS UNDERGOING LAPAROSCOPICNEPHRECTOMY

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KAMRANMANESH MOHAMMADREZA; GHARAEI BABAK; AGHAMOHAMMADI HOMAYOUN; JAFARI ALIREZA; POOR ZAMANI MAHTAB; ROODNESHIN FATEMEH; MAHMOODI MARYAM; DADKHAH PAYMAN

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Journal: JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE Year:2015 | Volume:37 | Issue:4 (92) Page(s): 0-0

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Title

ANALGESIC EFFECTS OF KETAMINE VS. DEXMEDETOMIDINE ON OPIOID ABUSERS UNDERGOING LAPAROSCOPICNEPHRECTOMY

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Keywords

KETAMINEQ3

DEXMEDETOMIDINEQ1

OPIOID SPARING EFFECTQ2

OPIUM ABUSERQ2

Abstract

Background: DEXMEDETOMIDINE has been used differently as a component ofpain management and resulted in various outcomes. KETAMINE was effective in pain relief of opioid addicts. In this study we compared low bolus KETAMINE and DEXMEDETOMIDINE injection on pain outcomes of addict patients undergoing laparoscopic nephrectomy.Methods: One hundred and seven addict patients candidate for laparoscopicnephrectomywereenrolled. They should havehad daily opioid consumption for at least 6 weeks. They were randomly allocated to receive KETAMINE (group K) or DEXMEDETOMIDINE (group D). Both groups received nearly the same anesthetic protocol with remifentanil infusion. Intra-operative remifentanil requirement (primary outcome), post-operative opioid consumption and opioid complications (secondary outcomes) were compared between groups.Results: Opioid requirement was significantly different between groups. Intraoperative remifentanil consumption in group K was 496±34 mg while 580±108 mg in group D (P<0.001). Post-operative opioid requirement was 4±1 mg for group K and 9±3 mg for group D (p<0.001). Complications were not statistically different.Conclusion: Intra and postoperative opioid consumption was statistically significantly reduced by KETAMINE compared to DEXMEDETOMIDINE.

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APA: Copy

KAMRANMANESH, MOHAMMADREZA, GHARAEI, BABAK, AGHAMOHAMMADI, HOMAYOUN, JAFARI, ALIREZA, POOR ZAMANI, MAHTAB, ROODNESHIN, FATEMEH, MAHMOODI, MARYAM, & DADKHAH, PAYMAN. (2015). ANALGESIC EFFECTS OF KETAMINE VS. DEXMEDETOMIDINE ON OPIOID ABUSERS UNDERGOING LAPAROSCOPICNEPHRECTOMY. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 37(4 (92) ), 0-0. SID. https://sid.ir/paper/63475/en

Vancouver: Copy

KAMRANMANESH MOHAMMADREZA, GHARAEI BABAK, AGHAMOHAMMADI HOMAYOUN, JAFARI ALIREZA, POOR ZAMANI MAHTAB, ROODNESHIN FATEMEH, MAHMOODI MARYAM, DADKHAH PAYMAN. ANALGESIC EFFECTS OF KETAMINE VS. DEXMEDETOMIDINE ON OPIOID ABUSERS UNDERGOING LAPAROSCOPICNEPHRECTOMY. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2015;37(4 (92) ):0-0. Available from: https://sid.ir/paper/63475/en

IEEE: Copy

MOHAMMADREZA KAMRANMANESH, BABAK GHARAEI, HOMAYOUN AGHAMOHAMMADI, ALIREZA JAFARI, MAHTAB POOR ZAMANI, FATEMEH ROODNESHIN, MARYAM MAHMOODI, and PAYMAN DADKHAH, “ANALGESIC EFFECTS OF KETAMINE VS. DEXMEDETOMIDINE ON OPIOID ABUSERS UNDERGOING LAPAROSCOPICNEPHRECTOMY,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 37, no. 4 (92) , pp. 0–0, 2015, [Online]. Available: https://sid.ir/paper/63475/en

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