SIZE EFFECTS OF GOLD AND IRON NANOPARTICLES ON RADIATION DOSE ENHANCEMENT IN BRACHYTHERAPY AND TELETHERAPY: A MONTE CARLO STUDY

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EZZATI AHAD OLLAH; MAHDAVI SEYED RABI; MOUSAVIE ANIJDAN HOSSEIN

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Journal: IRANIAN JOURNAL OF MEDICAL PHYSICS Year:2014 | Volume:11 | Issue:2-3 Page(s): 253-259

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Title

SIZE EFFECTS OF GOLD AND IRON NANOPARTICLES ON RADIATION DOSE ENHANCEMENT IN BRACHYTHERAPY AND TELETHERAPY: A MONTE CARLO STUDY

Author(s)

EZZATI AHAD OLLAH | MAHDAVI SEYED RABI | MOUSAVIE ANIJDAN HOSSEIN | Issue Writer Certificate

Keywords

BRACHYTHERAPY

DOSE ENHANCEMENT FACTOR

MONTE CARLO

NANOPARTICLE

Abstract

Introduction: In this study, we aimed to calculate DOSE ENHANCEMENT FACTOR (DEF) for gold (Au) and iron (Fe) NANOPARTICLEs (NPs) in BRACHYTHERAPY and teletherapy, using MONTE CARLO (MC) method.Materials and Methods: In this study, a new algorithm was introduced to calculate dose enhancement by AuNPs and FeNPs for Iridium-192 (Ir-192) BRACHYTHERAPY and Cobalt-60 (Co-60) teletherapy sources, using the MC method. In this algorithm, the semi-random distribution of NPs was used instead of the regular distribution. Diameters were assumed to be 15, 30, and 100 nm in BRACHYTHERAPY and 15 and 30 nm in teletherapy. MONTE CARLO MCNP4C code was used for simulations, and NP density values were 0.107 mg/ml and 0.112 mg/ml in BRACHYTHERAPY and teletherapy, respectively.Results: AuNPs significantly enhanced the radiation dose in BRACHYTHERAPY (approximately 60%), and 100 nm diameter NPs showed the most uniform dose distribution. AuNPs had an insignificant effect on teletherapy radiation field, with a dose enhancement ratio of 3% (about the calculation uncertainty) or less. In addition, FeNPs had an insignificant effect on both BRACHYTHERAPY and teletherapy radiation fields. FeNPs dose enhancement was 3% in BRACHYTHERAPY and 6% (about the calculation uncertainty) or less in teletherapy.Conclusion: It can be concluded that AuNPs can significantly increase the absorbed dose in BRACHYTHERAPY; however, FeNPs do not have a noticeable effect on the absorbed dose. Overall, AuNPs and FeNPs cannot increase the absorbed dose for the Co-60 teletherapy source.

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APA: Copy

EZZATI, AHAD OLLAH, MAHDAVI, SEYED RABI, & MOUSAVIE ANIJDAN, HOSSEIN. (2014). SIZE EFFECTS OF GOLD AND IRON NANOPARTICLES ON RADIATION DOSE ENHANCEMENT IN BRACHYTHERAPY AND TELETHERAPY: A MONTE CARLO STUDY. IRANIAN JOURNAL OF MEDICAL PHYSICS, 11(2-3), 253-259. SID. https://sid.ir/paper/634864/en

Vancouver: Copy

EZZATI AHAD OLLAH, MAHDAVI SEYED RABI, MOUSAVIE ANIJDAN HOSSEIN. SIZE EFFECTS OF GOLD AND IRON NANOPARTICLES ON RADIATION DOSE ENHANCEMENT IN BRACHYTHERAPY AND TELETHERAPY: A MONTE CARLO STUDY. IRANIAN JOURNAL OF MEDICAL PHYSICS[Internet]. 2014;11(2-3):253-259. Available from: https://sid.ir/paper/634864/en

IEEE: Copy

AHAD OLLAH EZZATI, SEYED RABI MAHDAVI, and HOSSEIN MOUSAVIE ANIJDAN, “SIZE EFFECTS OF GOLD AND IRON NANOPARTICLES ON RADIATION DOSE ENHANCEMENT IN BRACHYTHERAPY AND TELETHERAPY: A MONTE CARLO STUDY,” IRANIAN JOURNAL OF MEDICAL PHYSICS, vol. 11, no. 2-3, pp. 253–259, 2014, [Online]. Available: https://sid.ir/paper/634864/en

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