COMPARATIVE STUDYOF HEMODYNAMIC CHANGES DUE TO INDUCTION OF ANESTHESIA WITH KETAMINE ALONE VS. KETAMINE AND PROPOFOL

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ABBASIVASH R.; HESHMATI F.; ZEYNALI M.B.; NOUROUZINIA H.; HOSEINZADEH A.R.

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Journal: Studies in Medical Sciences Year:2004 | Volume:15 | Issue:1 Page(s): 26-32

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Title

COMPARATIVE STUDYOF HEMODYNAMIC CHANGES DUE TO INDUCTION OF ANESTHESIA WITH KETAMINE ALONE VS. KETAMINE AND PROPOFOL

Author(s)

Keywords

INDUCTION OF ANESTHESIAQ3

KETAMINEQ3

PROPOFOLQ3

HERNODYNAMICQ2

Abstract

Background & Aim: The aim of this study is reduction of hemodynamic changes during induction of general anesthesia by co-administration of intravenouse KETAMINE and PROPOFOL. Materials & Methods: In this clinical trial, we studied sixty, 20-40 yrs old patients, which randomly divided in two equal groups, control and study. At first, under equal conditions, prior to any drug administration, the patient's systolic, diastolic and mean arterial pressures and heart rate were detected (basal parameters). In the control group, intavenous KETAMINE (2 mg/kg) and in study group, intravenous KETAMINE plus PROPOFOL (each 1 mg/kg) administered for induction of general anesthesia. Then, the mentioned hemodynamic parameters were measured in both groups, at the times of 1 minute after induction and 1, 3, 5, 10 and 15 minute after intubation. The changes of measured indexes were analyzed. Results: In all cases (except for changes in heart rate), in study group, cardiovascular indexes reduced from basal parameters to less than 20%, and in control group, these indexes increased from basal parameters to greater than 30% (p<0.05). Discussion: If there are no contraindications for KETAMINE and PROPOFOL administration, and the a little hemodynamic change be desirable (e.g. ischemic heart disease), we can use the combination of KETAMINE and PROPOFOL for induction of general anesthesia.

Cites

EFFECT OF ADDING KETAMINE TO PROPOFOL INFUSION ON HEMODYNAMICS AND RECOVERY TIME OF PATIENTS UNDER CATARACT SURGERY

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APA: Copy

ABBASIVASH, R., HESHMATI, F., ZEYNALI, M.B., NOUROUZINIA, H., & HOSEINZADEH, A.R.. (2004). COMPARATIVE STUDYOF HEMODYNAMIC CHANGES DUE TO INDUCTION OF ANESTHESIA WITH KETAMINE ALONE VS. KETAMINE AND PROPOFOL . STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 15(1), 26-32. SID. https://sid.ir/paper/63507/en

Vancouver: Copy

ABBASIVASH R., HESHMATI F., ZEYNALI M.B., NOUROUZINIA H., HOSEINZADEH A.R.. COMPARATIVE STUDYOF HEMODYNAMIC CHANGES DUE TO INDUCTION OF ANESTHESIA WITH KETAMINE ALONE VS. KETAMINE AND PROPOFOL . STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2004;15(1):26-32. Available from: https://sid.ir/paper/63507/en

IEEE: Copy

R. ABBASIVASH, F. HESHMATI, M.B. ZEYNALI, H. NOUROUZINIA, and A.R. HOSEINZADEH, “COMPARATIVE STUDYOF HEMODYNAMIC CHANGES DUE TO INDUCTION OF ANESTHESIA WITH KETAMINE ALONE VS. KETAMINE AND PROPOFOL ,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 15, no. 1, pp. 26–32, 2004, [Online]. Available: https://sid.ir/paper/63507/en

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