EFFECT OF ADDING KETAMINE TO PROPOFOL INFUSION ON HEMODYNAMICS AND RECOVERY TIME OF PATIENTS UNDER CATARACT SURGERY

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YAZDI BIJAN; KHALILI MOHAMMAD; TALEBI HOUSHANG; FOTOVAT ALI REZA; NIKAEEN AREZOU

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Journal: Journal of Anesthesiology and Pain Year:2011 | Volume:1 | Issue:4 Page(s): 10-23

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Title

EFFECT OF ADDING KETAMINE TO PROPOFOL INFUSION ON HEMODYNAMICS AND RECOVERY TIME OF PATIENTS UNDER CATARACT SURGERY

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Keywords

HEMODYNAMICQ2

ANESTHESIAQ3

PROPOFOLQ3

KETAMINEQ3

CATARACTQ3

Abstract

Introduction: According to the importance of HEMODYNAMIC stability during ANESTHESIA, usage of drugs and technics which change the HEMODYNAMIC in a minimum rate has become one of the most important purposes. Widely spread usage of PROPOFOL for sedation in CATARACT surgery made us to evaluate the effect of KETAMINE, which in itself has sympathetic effects, in usage accompaning with PROPOFOL.Materials and Methods: In a double blinded clinical trial 110 patients whom were candidate for CATARACT surgery were divided in two groups accidentally. After dripping topical analgesic drop and intravenous fentanyl injection 1mcg/kg: In one of the groups 0.25 mg/kg KETAMINE and in the other one 2cc normal saline were injected. PROPOFOL infusion was started up to reaching to Ramsy score 3. Blood pressure, pulse rate and arterial O2 saturation were measured before and after injection of drug or placebo and also every 2 minutes for 10 minutes and the every 5 minutes up to end of surgery and transportation to recovery. Recovery time and PROPOFOL prescribed dosage were also measured. The results were analyzed with SPSS software.Results: The average of systolic blood pressure and diastolic blood pressure was higher in 2 and 6 minutes and diastolic blood pressure was higher in minute 4 in KETAMINE group after injection. After injection and 2 minute later the average of pulse rate was higher in KETAMINE group. Also the usage of PROPOFOL in KETAMINE group was less and the recovery time was longer.Conclusion: Although the recovery time in KETAMINE – PROPOFOL usage is longer but it provides a better stability in patients HEMODYNAMIC and also reduces the PROPOFOL dosage.

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APA: Copy

YAZDI, BIJAN, KHALILI, MOHAMMAD, TALEBI, HOUSHANG, FOTOVAT, ALI REZA, & NIKAEEN, AREZOU. (2011). EFFECT OF ADDING KETAMINE TO PROPOFOL INFUSION ON HEMODYNAMICS AND RECOVERY TIME OF PATIENTS UNDER CATARACT SURGERY. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), 1(4), 10-23. SID. https://sid.ir/paper/216321/en

Vancouver: Copy

YAZDI BIJAN, KHALILI MOHAMMAD, TALEBI HOUSHANG, FOTOVAT ALI REZA, NIKAEEN AREZOU. EFFECT OF ADDING KETAMINE TO PROPOFOL INFUSION ON HEMODYNAMICS AND RECOVERY TIME OF PATIENTS UNDER CATARACT SURGERY. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN)[Internet]. 2011;1(4):10-23. Available from: https://sid.ir/paper/216321/en

IEEE: Copy

BIJAN YAZDI, MOHAMMAD KHALILI, HOUSHANG TALEBI, ALI REZA FOTOVAT, and AREZOU NIKAEEN, “EFFECT OF ADDING KETAMINE TO PROPOFOL INFUSION ON HEMODYNAMICS AND RECOVERY TIME OF PATIENTS UNDER CATARACT SURGERY,” JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), vol. 1, no. 4, pp. 10–23, 2011, [Online]. Available: https://sid.ir/paper/216321/en

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