MEAN PLATELET VOLUME AS A NEGATIVE MARKER OF INFLAMMATION IN CHILDREN WITH ROTAVIRUS GASTROENTERITIS

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TANJU CELIK; EKREM GULER; EMEL ATAS BERKSOY; ARSLAN NUR

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Journal: Iranian Journal of Pediatrics Year:2014 | Volume:24 | Issue:5 Page(s): 617-622

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Title

MEAN PLATELET VOLUME AS A NEGATIVE MARKER OF INFLAMMATION IN CHILDREN WITH ROTAVIRUS GASTROENTERITIS

Author(s)

TANJU CELIK | EKREM GULER | EMEL ATAS BERKSOY | ARSLAN NUR | Issue Writer Certificate

Keywords

CHILD

GASTROENTERITIS

INFLAMMATION

MEAN PLATELET VOLUME

ROTAVIRUS

Abstract

Objective: MEAN PLATELET VOLUME (MPV) is a determinant of INFLAMMATION. The aim of the present study was to investigate the MPV levels in CHILDren with ROTAVIRUS GASTROENTERITIS and to evaluate the possible relationship between MPV and severity of GASTROENTERITIS.Methods: CHILDren diagnosed with acute ROTAVIRUS GASTROENTERITIS and healthy controls were enrolled in this study. Patients were classified into three disease severity groups based on their Vesikari score (<7 mild, 7-10 moderate and>11 severe). ROTAVIRUS was determined in fresh stool samples using ELISA test. Leukocyte and platelet counts, MPV and C-reactive protein (CRP) levels were assessed for all CHILDren.Findings: A total of 151 patients with ROTAVIRUS GASTROENTERITIS (mean age 2.41±0.14 years) and 80 healthy controls (mean age 2.63±0.22 years, P=0.129) were enrolled. MPV levels of CHILDren with ROTAVIRUS GASTROENTERITIS were significantly lower than those of healthy peers (7.48±0.04 vs 7.79±0.07 fl, P=0.000). MPV levels were not significantly different among three GASTROENTERITIS groups. GASTROENTERITIS score was positively correlated with leukocyte (r=0.670, P<0.01) and platelet count (r=0.159, P<0.05) and CRP level (r=0.256, P<0.01) in patients group. MPV was inversely correlated with platelet count. There was no significant correlation between MPV and GASTROENTERITIS score.Conclusion: MPV levels were significantly lower in CHILDren with ROTAVIRUS GASTROENTERITIS compared to controls. MPV can be used as a negative acute phase reactant in CHILDren with ROTAVIRUS GASTROENTERITIS.

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APA: Copy

TANJU, CELIK, EKREM, GULER, EMEL, ATAS BERKSOY, & ARSLAN, NUR. (2014). MEAN PLATELET VOLUME AS A NEGATIVE MARKER OF INFLAMMATION IN CHILDREN WITH ROTAVIRUS GASTROENTERITIS. IRANIAN JOURNAL OF PEDIATRICS, 24(5), 617-622. SID. https://sid.ir/paper/637516/en

Vancouver: Copy

TANJU CELIK, EKREM GULER, EMEL ATAS BERKSOY, ARSLAN NUR. MEAN PLATELET VOLUME AS A NEGATIVE MARKER OF INFLAMMATION IN CHILDREN WITH ROTAVIRUS GASTROENTERITIS. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2014;24(5):617-622. Available from: https://sid.ir/paper/637516/en

IEEE: Copy

CELIK TANJU, GULER EKREM, ATAS BERKSOY EMEL, and NUR ARSLAN, “MEAN PLATELET VOLUME AS A NEGATIVE MARKER OF INFLAMMATION IN CHILDREN WITH ROTAVIRUS GASTROENTERITIS,” IRANIAN JOURNAL OF PEDIATRICS, vol. 24, no. 5, pp. 617–622, 2014, [Online]. Available: https://sid.ir/paper/637516/en

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