USE OF MYCOPHENOLATE MOFETIL (MMF) IN A CASE WITH SEVERE HENOCH- SCH..ONLEIN NEPHRITIS

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NIKIBAKHSH A.A.; MAHMOUDZADEH HASHEM; KARAMYAR M.; AGHAYAR MAKOUEI A.; NOUROUZI MEHRAN

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Journal: Studies in Medical Sciences Year:2009 | Volume:20 | Issue:1 Page(s): 71-74

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Title

USE OF MYCOPHENOLATE MOFETIL (MMF) IN A CASE WITH SEVERE HENOCH- SCH..ONLEIN NEPHRITIS

Author(s)

Keywords

SCHOONLEINQ3

HENOCH NEPHRITISQ3

MYCOPHENOLATE MOFETILQ3

GLOMERULONEPHRITISQ3

CHILDRENQ3

Abstract

Renal involvement is one of the most serious sequela of Henoch-Sch..onlein purpura. The presence of proteinuria (nephritic range) and hematuria is also associated with progression to renal insufficiency.In fifty percent of patients who display a combination of nephritis-nephrotic symptoms, end-stage disease develops. Pharmacologic treatments are controversial, and more research needs to be done to clarify therapeutic regimens.A five years old child with clacic signs and symptoms of Henoch-Sch..onlein purpura and sever renal involvement (combination of nephritis-nephrotic syndrome) was treated succesfuly by MYCOPHENOLATE MOFETIL. This case was resistant to methyl prednisolon and cyclophosphamid pulse.Mycophenolate mofetil is an immunosuppressive agent which is used in many autoimmune disorders such as lupus nephritis, vasculitis, necrotizing GLOMERULONEPHRITIS, corticosteroid resistant glomerunephritis and IgA nephropathy, but there are no enough data on the use of mycophenolate mofeti in complications of Henoch-Sch..onlein diseases. Herein, we report successful use of MYCOPHENOLATE MOFETIL in a case with severe Henoch Sch..onlein- nephritis resistant to both methylprednisolone and cyclophosphamid pulse.

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APA: Copy

NIKIBAKHSH, A.A., MAHMOUDZADEH, HASHEM, KARAMYAR, M., AGHAYAR MAKOUEI, A., & NOUROUZI, MEHRAN. (2009). USE OF MYCOPHENOLATE MOFETIL (MMF) IN A CASE WITH SEVERE HENOCH- SCH^..ONLEIN NEPHRITIS. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 20(1), 71-74. SID. https://sid.ir/paper/63906/en

Vancouver: Copy

NIKIBAKHSH A.A., MAHMOUDZADEH HASHEM, KARAMYAR M., AGHAYAR MAKOUEI A., NOUROUZI MEHRAN. USE OF MYCOPHENOLATE MOFETIL (MMF) IN A CASE WITH SEVERE HENOCH- SCH^..ONLEIN NEPHRITIS. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2009;20(1):71-74. Available from: https://sid.ir/paper/63906/en

IEEE: Copy

A.A. NIKIBAKHSH, HASHEM MAHMOUDZADEH, M. KARAMYAR, A. AGHAYAR MAKOUEI, and MEHRAN NOUROUZI, “USE OF MYCOPHENOLATE MOFETIL (MMF) IN A CASE WITH SEVERE HENOCH- SCH^..ONLEIN NEPHRITIS,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 20, no. 1, pp. 71–74, 2009, [Online]. Available: https://sid.ir/paper/63906/en

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