ASSESSMENT OF THE DEMOGRAPHIC DATA AND EXPRESSION OF THE CELLULAR MARKERS CD20, CD30, CD15 IN REEDSTERNBERG CELLS, ALONG WITH THEIR RELATION TO STAGING IN HODGKIN LYMPHOMA CASES OF IMAM KHOMEINI HOSPITAL OF URMIA CITY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

IILKHANIZADEH BEHROUZ; MAZLOMI POOYA; EISHI ALI; YEKTA ZAHRA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Studies in Medical Sciences Year:2013 | Volume:24 | Issue:2 Page(s): 146-153

Download Full-Text

Persian Verion

View:

723

Download:

Cites:

Information Journal Paper

Title

ASSESSMENT OF THE DEMOGRAPHIC DATA AND EXPRESSION OF THE CELLULAR MARKERS CD20, CD30, CD15 IN REEDSTERNBERG CELLS, ALONG WITH THEIR RELATION TO STAGING IN HODGKIN LYMPHOMA CASES OF IMAM KHOMEINI HOSPITAL OF URMIA CITY

Author(s)

IILKHANIZADEH BEHROUZ | MAZLOMI POOYA | EISHI ALI | YEKTA ZAHRA | Issue Writer Certificate

Keywords

HODGKIN LYMPHOMAQ2

PROGNOSISQ3

IMMUNOHISTOCHEMISTERYQ3

Abstract

Background & Aims: Staging plays an important role both in defining the PROGNOSIS of Hodgkin disease and choosing the best treatment regimen. Moreover, factors such as age, gender, WBC>15000, Hb<10.5mg/dl, and B-symptoms has been also recommended to be influential in the PROGNOSIS, which were not completely successful. Nevertheless many studies have investigated the correlation between cellular markers and the PROGNOSIS of HODGKIN LYMPHOMA. Among them, CD15, CD30 and CD15 were the most studied markers. In this study we evaluated both the demographic findings and frequencies of expression of the markers CD20, CD30, CD15 and their relation to Staging in HODGKIN LYMPHOMA cases of Imam Khomeini hospital of Urmia, Iran.Materials & Methods: Retrospectively 66 eligible patients from 2005 to 2010 entered the study. For evaluation of the markers CD20, CD30, CD15, IMMUNOHISTOCHEMISTERY preformed on lymph-nods’ paraffin embedded blocks. Staging, demographic findings and Immunohistochemical findings analyzed for possible correlation between Staging and other parameters. In all cases SPSS software and Fisher Exact test were used for statistical analyzes.Results: In our study, median age of patients was 30.6±17 years old and 54.5% of patients were admitted with higher stages of the disease, which is similar to results of other studies in the country. Respectively, 63.6%, 90.9% and 18.2% of cases expressed cellular markers CD15, CD30 and CD20.Conclusion Furthermore, statistical analysis revealed that CD15 was inversely correlated with disease stage. (P=0.027). In contrast, we didn’t find any relation between Staging with neither CD20 nor CD30 positivity that possibly offers the latter markers were not related to disease PROGNOSIS.(P=0.482, P=0.376).

Cites

No record.

References

No record.

Cite

APA: Copy

IILKHANIZADEH, BEHROUZ, MAZLOMI, POOYA, EISHI, ALI, & YEKTA, ZAHRA. (2013). ASSESSMENT OF THE DEMOGRAPHIC DATA AND EXPRESSION OF THE CELLULAR MARKERS CD20, CD30, CD15 IN REEDSTERNBERG CELLS, ALONG WITH THEIR RELATION TO STAGING IN HODGKIN LYMPHOMA CASES OF IMAM KHOMEINI HOSPITAL OF URMIA CITY. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 24(2), 146-153. SID. https://sid.ir/paper/63995/en

Vancouver: Copy

IILKHANIZADEH BEHROUZ, MAZLOMI POOYA, EISHI ALI, YEKTA ZAHRA. ASSESSMENT OF THE DEMOGRAPHIC DATA AND EXPRESSION OF THE CELLULAR MARKERS CD20, CD30, CD15 IN REEDSTERNBERG CELLS, ALONG WITH THEIR RELATION TO STAGING IN HODGKIN LYMPHOMA CASES OF IMAM KHOMEINI HOSPITAL OF URMIA CITY. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2013;24(2):146-153. Available from: https://sid.ir/paper/63995/en

IEEE: Copy

BEHROUZ IILKHANIZADEH, POOYA MAZLOMI, ALI EISHI, and ZAHRA YEKTA, “ASSESSMENT OF THE DEMOGRAPHIC DATA AND EXPRESSION OF THE CELLULAR MARKERS CD20, CD30, CD15 IN REEDSTERNBERG CELLS, ALONG WITH THEIR RELATION TO STAGING IN HODGKIN LYMPHOMA CASES OF IMAM KHOMEINI HOSPITAL OF URMIA CITY,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 24, no. 2, pp. 146–153, 2013, [Online]. Available: https://sid.ir/paper/63995/en

Related Journal Papers