DETACHMENT, CULTIVATION AND DEFFRENTIATION OF BULGE STEM HAIR FOLLICAL CELLS TO NEURAL CELLS

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NAJAFZADEH NOROOZ; NOBAKHT MALIHEH; ASALGOO SARA

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Journal: Studies in Medical Sciences Year:2012 | Volume:23 | Issue:1 Page(s): 66-72

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Information Journal Paper

Title

DETACHMENT, CULTIVATION AND DEFFRENTIATION OF BULGE STEM HAIR FOLLICAL CELLS TO NEURAL CELLS

Author(s)

NAJAFZADEH NOROOZ | NOBAKHT MALIHEH | ASALGOO SARA | Issue Writer Certificate

Keywords

HAIR FOLLICLEQ1

STEM CELLQ2

RAT HAIR FOLLICLEQ2

CELL CULTUREQ3

DIFFERENTIATIONQ3

Abstract

Background & Aims: Throughout life, STEM CELLs make new cells in various tissues.Bulge region of HAIR FOLLICLE indicated as sources of STEM CELLs for along times but little studies done in vitro to characterize rat bulge HAIR FOLLICLE STEM CELLs.Materials & Methods: In this study bulge cells of rat HAIR FOLLICLE were isolated and were cultured, then morphological features of differentiated cells were studied. Also, rat HAIR FOLLICLE cells were assessed one and three weeks after cultivation.Results: The result showed that two days after cell attachment to floor of plates, the cells initiate to proliferation and migration. Growth curve showed that the rate of cell proliferation at day 8 reaches its maximum level. After a week of CELL CULTURE, they had good power but after detachment were limited reproduced. Most cells in high cell density conditions and NT- 3 treated media differentiated to neural and glial lineage.Conclusion: Results showed that cultivated rat bulge cells, have high proliferative potential, and also could change to neural and glial like cells.

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APA: Copy

NAJAFZADEH, NOROOZ, NOBAKHT, MALIHEH, & ASALGOO, SARA. (2012). DETACHMENT, CULTIVATION AND DEFFRENTIATION OF BULGE STEM HAIR FOLLICAL CELLS TO NEURAL CELLS. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 23(1), 66-72. SID. https://sid.ir/paper/64091/en

Vancouver: Copy

NAJAFZADEH NOROOZ, NOBAKHT MALIHEH, ASALGOO SARA. DETACHMENT, CULTIVATION AND DEFFRENTIATION OF BULGE STEM HAIR FOLLICAL CELLS TO NEURAL CELLS. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2012;23(1):66-72. Available from: https://sid.ir/paper/64091/en

IEEE: Copy

NOROOZ NAJAFZADEH, MALIHEH NOBAKHT, and SARA ASALGOO, “DETACHMENT, CULTIVATION AND DEFFRENTIATION OF BULGE STEM HAIR FOLLICAL CELLS TO NEURAL CELLS,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 23, no. 1, pp. 66–72, 2012, [Online]. Available: https://sid.ir/paper/64091/en

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