THE ROLE OF DECREASINGGASTRICACIDITY AND PREVENTIONOF GASTREROESOPHAGEAL REFLUX, IN REDUCING THE INCIDENCE OF PHARYNGO-CUTANEOUSFISTULA FOLLOWINGLARYNGECTOMYIN PATIENTS WITH LARYNGEALCARCINOMA

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KHADEMI B.; GANDOMI B.

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Title

THE ROLE OF DECREASINGGASTRICACIDITY AND PREVENTIONOF GASTREROESOPHAGEAL REFLUX, IN REDUCING THE INCIDENCE OF PHARYNGO-CUTANEOUSFISTULA FOLLOWINGLARYNGECTOMYIN PATIENTS WITH LARYNGEALCARCINOMA

Author(s)

KHADEMI B. | GANDOMI B. | Issue Writer Certificate

Keywords

GASTROESOPHAGEAL REFLUX PROPHYLAXISQ4

PHARYNGOCUTANEOUS FISTULAQ4

LARYNGECTOMYQ3

LARYNGEAL CANCERQ4

Abstract

Introduction: PHARYNGOCUTANEOUS FISTULA is a serious complication following LARYNGECTOMY. Gastric and reflux seems to be a predisposing factor. Gastric acid can damage laryngopharyngeal mucosa and postpone mucosal repair. In this study, the role of prophylaxis against gasteroesophageal reflux in decreasing PHARYNGOCUTANEOUS FISTULA following LARYNGECTOMY, is evaluated.Materials & Methods: During a four year period) 56 laryngectomies were peifonned in the Khalili Hospital. From these) 30 patients received anti reflux prophylaxis including metoclopromide (10mg, iv, q6h) and cimetidine (200mg, iv, q6h) from 24 hour before surgery and continued during their hospital course (study group) and 26 patients did not receive anti reflux regimen (control group). Incidence of fistula in the two group was evaluated.Results: The incidence of PHARYNGOCUTANEOUS FISTULA in the control and study groups was 34.6% and 11% respectively. Discussion: This study supports the role of GASTROESOPHAGEAL REFLUX PROPHYLAXIS in decreasing the incidence of PHARYNGOCUTANEOUS FISTULA following LARYNGECTOMY in patients with laryngeal carcinoma.

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APA: Copy

KHADEMI, B., & GANDOMI, B.. (2001). THE ROLE OF DECREASINGGASTRICACIDITY AND PREVENTIONOF GASTREROESOPHAGEAL REFLUX, IN REDUCING THE INCIDENCE OF PHARYNGO-CUTANEOUSFISTULA FOLLOWINGLARYNGECTOMYIN PATIENTS WITH LARYNGEALCARCINOMA. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 12(3), 271-277. SID. https://sid.ir/paper/64135/en

Vancouver: Copy

KHADEMI B., GANDOMI B.. THE ROLE OF DECREASINGGASTRICACIDITY AND PREVENTIONOF GASTREROESOPHAGEAL REFLUX, IN REDUCING THE INCIDENCE OF PHARYNGO-CUTANEOUSFISTULA FOLLOWINGLARYNGECTOMYIN PATIENTS WITH LARYNGEALCARCINOMA. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2001;12(3):271-277. Available from: https://sid.ir/paper/64135/en

IEEE: Copy

B. KHADEMI, and B. GANDOMI, “THE ROLE OF DECREASINGGASTRICACIDITY AND PREVENTIONOF GASTREROESOPHAGEAL REFLUX, IN REDUCING THE INCIDENCE OF PHARYNGO-CUTANEOUSFISTULA FOLLOWINGLARYNGECTOMYIN PATIENTS WITH LARYNGEALCARCINOMA,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 12, no. 3, pp. 271–277, 2001, [Online]. Available: https://sid.ir/paper/64135/en

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