ANTIBIOTIC RESISTANCE PROFILES OF SALMONELL ASTRAINS ISOLATED IN THERAPEUTIC CENTERS OF TEHRAN

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MAHDAVI F.M.; HAKIMI SH.; GHAZI SAEIDI KIOUMARS

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Journal: Studies in Medical Sciences Year:2002 | Volume:13 | Issue:2 Page(s): 154-163

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Title

ANTIBIOTIC RESISTANCE PROFILES OF SALMONELL ASTRAINS ISOLATED IN THERAPEUTIC CENTERS OF TEHRAN

Author(s)

MAHDAVI F.M. | HAKIMI SH. | GHAZI SAEIDI KIOUMARS | Issue Writer Certificate

Keywords

ANTIBIOTIC RESISTANCEQ3

SALMONELLAQ2

LNTESTINAL INFECTIONQ4

Abstract

Background and objectives: The infections resulting from SALMONELLA typhi and non typhi SALMONELLA are still of special significance in many parts of the world especially in developing countries. Different types of SALMONELLA have increasingly become resistant to the common antibiotics used in therapy. Our main objective was to study of ANTIBIOTIC RESISTANCE Pattern of isolated SALMONELLA strains from treatment centers in Iran and other countries, so that effective measures could be taken in the treatment of SALMONELLA infections. Methods: One hundred SALMONELLA strains isolated from different clinical samples including faces, blood or CSF, bile, vamil and urine were studied. The clinical samples were cultured in the selective and differential media. Using biochemical tests, the strains were identified and the SALMONELLA antiserum (bioMerieux) was used. Sensitivity tests of the isolated strains were carried out using the disc-agar diffusion method. Finding: Of 100 strains 63% were isolated from blood, 26% from stool, 1%from CSF, 2% from bile, 7% from vomit. The isolated organisms were identified using biochemical and serologic tests and were arranged in the order of frequency of occurrence as: 40% strains SALMONELLA enteritidis, followed by Salmonalla typhi 23%, S typhimurium 19% and others. All of the tested strains, were sensitive to amikacin and ceftazidim, 98% of them were sensitive to Nalidixic acid, which were the highest percentages of sensitivity. Only 5% of strains were sensitive to streptomycin. Conclusion: The Prevalent SALMONELLA strains isolated in this study belonged to S enteritids, S typhi with pronounced presence of non typhi groups. All of the tested strains, 100% of them were sensitive to amikacin and ceftazidim. The comparison of these results with obtained results from similar studies in Iran and other countries shows that aminoglycosides, third generation cephalosprins and quinolones are at present the most promising drugs for the treatment of infections by SALMONELLA.

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ارزیابی اثر ضد میکروبی سفتازیدیم و مقایسه آن آنتی بیوتیک های دیگر بر روی سالمونلا

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APA: Copy

MAHDAVI, F.M., HAKIMI, SH., & GHAZI SAEIDI, KIOUMARS. (2002). ANTIBIOTIC RESISTANCE PROFILES OF SALMONELL ASTRAINS ISOLATED IN THERAPEUTIC CENTERS OF TEHRAN. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 13(2), 154-163. SID. https://sid.ir/paper/64228/en

Vancouver: Copy

MAHDAVI F.M., HAKIMI SH., GHAZI SAEIDI KIOUMARS. ANTIBIOTIC RESISTANCE PROFILES OF SALMONELL ASTRAINS ISOLATED IN THERAPEUTIC CENTERS OF TEHRAN. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2002;13(2):154-163. Available from: https://sid.ir/paper/64228/en

IEEE: Copy

F.M. MAHDAVI, SH. HAKIMI, and KIOUMARS GHAZI SAEIDI, “ANTIBIOTIC RESISTANCE PROFILES OF SALMONELL ASTRAINS ISOLATED IN THERAPEUTIC CENTERS OF TEHRAN,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 13, no. 2, pp. 154–163, 2002, [Online]. Available: https://sid.ir/paper/64228/en

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