The Effect of 6-Week Interval and Continuous Training with Zizphus Vulgaris Extract Supplementation on Hippocampus’ s BDNF Male Wistar Rats

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Bagherinia Azam; BANPARVARI MARYAM; MOGHARNASI MEHDI; SARIR HADI; Naderi Aynollah

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Journal: International Journal of Health Studies Year:2020 | Volume:6 | Issue:4 Page(s): 5-8

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Title

The Effect of 6-Week Interval and Continuous Training with Zizphus Vulgaris Extract Supplementation on Hippocampus’ s BDNF Male Wistar Rats

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Keywords

Interval training

Continuous training

Zizphus Vulgaris extract supplementation

Hippocampus’s BDNF

Male wistar rats

Abstract

Background: The aim of the study was to compare the effect of 6-week interval and Continuous training with Zizphus Vulgaris extract supplementation on the hippocampus’ s BDNF Male wistar rats. Methods: Among 36 male rats (250-350 gr), randomly after adjusting the body weight, 6 rats were separated as the control group. 30 rats were divided into 5 groups: Continuous group (n=6), interval group (n=6), continuous with Zizphus Vulgaris extract group (n=6), interval with Zizphus Vulgaris extract group (n=6) and Zizphus Vulgaris extract group (n=6). The training groups completed 8 weeks of the training program, 5 days/week according to protocol. The endurance continuous protocol includes running exercise on a treadmill for, 10 m/min, 10 min/day to up 16 m/min, 40 min/ day. Endurance interval protocol includes running exercise on a treadmill for, 5*4 min, with intensity 10 m/min to up 23 m/min, 52 min/ day. The Zizphus Vulgaris extract group, every 6 weeks, each rat consumed 400 mg/kg. day and 1. 5 mL. At the end of the intervention, the animals were euthanized and the hippocampus’ s BDNF was measured. Data were analyzed using one way ANOVA tests (Pvalue<0. 05). Results: Interval with the Zizphus Vulgaris extract group had significantly increased hippocampus’ s BDNF compared to control and Zizphus Vulgaris extract groups (respectively p=0. 01, p=0. 02). Other comparisons were not significant. Conclusions: Interval with Zizphus Vulgaris extract induce more effective favorable changes in the hippocampus’ s BDNF in male rats. Likely, that be the best Strategy to prevent negative effects on the hippocampus’ s BDNF decrease.

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APA: Copy

Bagherinia, Azam, BANPARVARI, MARYAM, MOGHARNASI, MEHDI, SARIR, HADI, & Naderi, Aynollah. (2020). The Effect of 6-Week Interval and Continuous Training with Zizphus Vulgaris Extract Supplementation on Hippocampus’ s BDNF Male Wistar Rats. INTERNATIONAL JOURNAL OF HEALTH STUDIES, 6(4), 5-8. SID. https://sid.ir/paper/646242/en

Vancouver: Copy

Bagherinia Azam, BANPARVARI MARYAM, MOGHARNASI MEHDI, SARIR HADI, Naderi Aynollah. The Effect of 6-Week Interval and Continuous Training with Zizphus Vulgaris Extract Supplementation on Hippocampus’ s BDNF Male Wistar Rats. INTERNATIONAL JOURNAL OF HEALTH STUDIES[Internet]. 2020;6(4):5-8. Available from: https://sid.ir/paper/646242/en

IEEE: Copy

Azam Bagherinia, MARYAM BANPARVARI, MEHDI MOGHARNASI, HADI SARIR, and Aynollah Naderi, “The Effect of 6-Week Interval and Continuous Training with Zizphus Vulgaris Extract Supplementation on Hippocampus’ s BDNF Male Wistar Rats,” INTERNATIONAL JOURNAL OF HEALTH STUDIES, vol. 6, no. 4, pp. 5–8, 2020, [Online]. Available: https://sid.ir/paper/646242/en

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