STATIN EFFICACY IN THE TREATMENT OF HEPATITIS C GENOTYPE I

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SHAVAKHI AHMAD; MINAKARI MOHAMAD; BIGHAMIAN AFSHIN; SADEGHIAN SINA; SHAVAKHI SARA; KHAMISI NASER; KHODADUSTAN MAHSA; TALEBI MAJID; ATAEI BEHROOZ

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS) Year:2014 | Volume:19 | Issue:SUPPLEMENT 1 Page(s): 1-4

Download Full-Text

View:

328

Download:

Cites:

Information Journal Paper

Title

STATIN EFFICACY IN THE TREATMENT OF HEPATITIS C GENOTYPE I

Author(s)

Keywords

HEPATITIS C

HYPERLIPIDEMIA

STATINS

Abstract

Background: Lipid metabolism is one of the HEPATITIS C virus (HCV) life cycle steps. STATINS can reduce cholesterol level and finally can decrease HCV replication. Thus, we assessed the effect of STATINS in combination with standard antiviral treatment on hyperlipidemic genotype I HCV infected patients.Materials and Methods: This study was a prospective clinical trial. 40 patients were selected from those referred to educational and Therapeutic Centers of Isfahan University of Medical Sciences from 2009 to 2010 with confirmed HCV viremia. All patients received Peg-interferon-a2a and ribavirin. 20 hyperlipidemic Patients received 20 mg atorvastatin nightly for 3 months and placebo was prescribed for 20 normolipidemic HCV infected patients as a control group. Liver enzymes and complete blood count were checked monthly and thyroid stimulating hormone was checked every 3 months. We also performed quantitative HCV-ribonucleic acid (RNA) test in 12th week of therapy, at the end of treatment and 6 months after therapy for all samples.Results: We didn’t find any significant differences in the mean of HCV-RNA numbers between statin and placebo groups in 12th week of treatment, in the end of treatment and 6 months after treatment (P>0.05).Conclusion: Atorvastatin has no effect on the mean of HCV viral load when we added it to standard treatment for HEPATITIS C infection. Further studies are necessary to examine the possible antiviral properties of STATINS and their potential role as adjuncts to standard HCV therapy.

Cites

No record.

References

No record.

Cite

APA: Copy

SHAVAKHI, AHMAD, MINAKARI, MOHAMAD, BIGHAMIAN, AFSHIN, SADEGHIAN, SINA, SHAVAKHI, SARA, KHAMISI, NASER, KHODADUSTAN, MAHSA, TALEBI, MAJID, & ATAEI, BEHROOZ. (2014). STATIN EFFICACY IN THE TREATMENT OF HEPATITIS C GENOTYPE I. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 19(SUPPLEMENT 1), 1-4. SID. https://sid.ir/paper/647090/en

Vancouver: Copy

SHAVAKHI AHMAD, MINAKARI MOHAMAD, BIGHAMIAN AFSHIN, SADEGHIAN SINA, SHAVAKHI SARA, KHAMISI NASER, KHODADUSTAN MAHSA, TALEBI MAJID, ATAEI BEHROOZ. STATIN EFFICACY IN THE TREATMENT OF HEPATITIS C GENOTYPE I. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2014;19(SUPPLEMENT 1):1-4. Available from: https://sid.ir/paper/647090/en

IEEE: Copy

AHMAD SHAVAKHI, MOHAMAD MINAKARI, AFSHIN BIGHAMIAN, SINA SADEGHIAN, SARA SHAVAKHI, NASER KHAMISI, MAHSA KHODADUSTAN, MAJID TALEBI, and BEHROOZ ATAEI, “STATIN EFFICACY IN THE TREATMENT OF HEPATITIS C GENOTYPE I,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 19, no. SUPPLEMENT 1, pp. 1–4, 2014, [Online]. Available: https://sid.ir/paper/647090/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops