EVALUATION OF OOGENESIS ASPECTS IN NEONATAL AND ADULT MICE AFTER TOLOALDOXIME TREATMENT

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FAZELTABAR MALEKSHAH MOHAMMAD; SEDIGHI MAHSA; PARIVAR KAZEM; MOHSENI KOUCHESFAHANI HOMA; BIGDELI MOHAMADALI

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Journal: Cell Journal (Yakhteh) Year:2015 | Volume:17 | Issue:3 (67) Page(s): 564-568

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Title

EVALUATION OF OOGENESIS ASPECTS IN NEONATAL AND ADULT MICE AFTER TOLOALDOXIME TREATMENT

Author(s)

Keywords

TOLOALDOXIME

OVARY

BALB/C MOUSE

FERTILITY

Abstract

Objective: Oximes are important materials in organic chemistry. Synparamethyl benzaldehyde oxime (TOLOALDOXIME) is structurally similar to other oximes, hence we have studied its effects on the neonatal and adult female Balb/c mice reproductive systems in order to provide a platform for future studies on the production of female contraceptive drugs.Materials and Methods: In experimental study, we studied the effects of TOLOALDOXIME on OVARY growth and gonadal hormones of neonatal and adult Balb/c mice. A regression model for prediction was presented.Results: The effects of TOLOALDOXIME on neonatal mice were more than adult mice.The greatest effect was on the number of Graafian follicles (59.6% in adult mice and 31.83% in neonatal mice). The least effect was on OVARY weight, and blood serum levels of follicle stimulating hormone (FSH) and luteinizing hormone (LH).Conclusion: According to the data obtained, TOLOALDOXIME can be considered an antipregnancy substance.

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References

EFFECTS OF DIFFERENT CRYOPROTECTANT COMBINATIONS ON PRIMORDIAL FOLLICLE SURVIVABILITY AND APOPTOSIS INCIDENCE AFTER VITRIFICATION OF WHOLE RAT OVARY

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APA: Copy

FAZELTABAR MALEKSHAH, MOHAMMAD, SEDIGHI, MAHSA, PARIVAR, KAZEM, MOHSENI KOUCHESFAHANI, HOMA, & BIGDELI, MOHAMADALI. (2015). EVALUATION OF OOGENESIS ASPECTS IN NEONATAL AND ADULT MICE AFTER TOLOALDOXIME TREATMENT. CELL JOURNAL (YAKHTEH), 17(3 (67)), 564-568. SID. https://sid.ir/paper/659887/en

Vancouver: Copy

FAZELTABAR MALEKSHAH MOHAMMAD, SEDIGHI MAHSA, PARIVAR KAZEM, MOHSENI KOUCHESFAHANI HOMA, BIGDELI MOHAMADALI. EVALUATION OF OOGENESIS ASPECTS IN NEONATAL AND ADULT MICE AFTER TOLOALDOXIME TREATMENT. CELL JOURNAL (YAKHTEH)[Internet]. 2015;17(3 (67)):564-568. Available from: https://sid.ir/paper/659887/en

IEEE: Copy

MOHAMMAD FAZELTABAR MALEKSHAH, MAHSA SEDIGHI, KAZEM PARIVAR, HOMA MOHSENI KOUCHESFAHANI, and MOHAMADALI BIGDELI, “EVALUATION OF OOGENESIS ASPECTS IN NEONATAL AND ADULT MICE AFTER TOLOALDOXIME TREATMENT,” CELL JOURNAL (YAKHTEH), vol. 17, no. 3 (67), pp. 564–568, 2015, [Online]. Available: https://sid.ir/paper/659887/en

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