A Case Report of Hyperphosphatasia Treated with Pamidronate

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Mirhosseini Naser Ali; TaghiyaR Sana; Saatchi Mahdieh

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Journal Paper

Paper Information

Journal: WORLD JOURNAL OF PERI AND NEONATOLOGY Year:2020 | Volume:3 | Issue:2 Page(s): 87-89

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Information Journal Paper

Title

A Case Report of Hyperphosphatasia Treated with Pamidronate

Author(s)

Mirhosseini Naser Ali | TaghiyaR Sana | Saatchi Mahdieh | Issue Writer Certificate

Keywords

Alkaline Phosphatase

Deformities

Hyperphosphatasia

Pamidronate

Abstract

Background: Hereditary Hyperphosphatasia is a congenital and rare disease with high bone turn over. The disease is defined with extremely elevated Alkaline Phosphatase levels. Neonates with Hyperphosphatasia are normal at birth but develop progressive long bone Deformities, fracture, vertebral collapse, skull enlargement due to massively thickened calvarium, and deafness. Case Presentation: Here, we described a male patient with progressive deformity in limbs and pain during walking that onset of symptoms was from age of two. The patient admitted to the Shahid Sadoughi Hospital, Yazd, was born from a non-consanguineous marriage. He was treated with Pamidronate until halt of the disease progression and followed up for 18 months. Conclusion: Bisphosphonate is the treatment of choice for Hyperphosphatasia because it can normalize bone turnover, improve growth rates, and skeletal quality.

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APA: Copy

Mirhosseini, Naser Ali, TaghiyaR, Sana, & Saatchi, Mahdieh. (2020). A Case Report of Hyperphosphatasia Treated with Pamidronate. WORLD JOURNAL OF PERI AND NEONATOLOGY, 3(2), 87-89. SID. https://sid.ir/paper/661159/en

Vancouver: Copy

Mirhosseini Naser Ali, TaghiyaR Sana, Saatchi Mahdieh. A Case Report of Hyperphosphatasia Treated with Pamidronate. WORLD JOURNAL OF PERI AND NEONATOLOGY[Internet]. 2020;3(2):87-89. Available from: https://sid.ir/paper/661159/en

IEEE: Copy

Naser Ali Mirhosseini, Sana TaghiyaR, and Mahdieh Saatchi, “A Case Report of Hyperphosphatasia Treated with Pamidronate,” WORLD JOURNAL OF PERI AND NEONATOLOGY, vol. 3, no. 2, pp. 87–89, 2020, [Online]. Available: https://sid.ir/paper/661159/en

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