PREVALENCE OF AMPC AND ESBL PRODUCING E. COLI AND ANTIBACTERIAL EFFECT OF ALLIM SATIVUM ON CLINICAL ISOLATES COLLECTED FROM ZAHEDAN HOSPITALS

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SHAYAN SARA; BOKAEIAN MOHAMMAD; SHAHRAKI SHAHRAM; SAEIDI SAEIDE

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Journal: Zahedan Journal of Research in Medical Sciences Year:2014 | Volume:16 | Issue:4 Page(s): 6-10

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Information Journal Paper

Title

PREVALENCE OF AMPC AND ESBL PRODUCING E. COLI AND ANTIBACTERIAL EFFECT OF ALLIM SATIVUM ON CLINICAL ISOLATES COLLECTED FROM ZAHEDAN HOSPITALS

Author(s)

SHAYAN SARA | BOKAEIAN MOHAMMAD | SHAHRAKI SHAHRAM | SAEIDI SAEIDE | Issue Writer Certificate

Keywords

AMPC β

LACTAMASES

ALLIM SATIVUM

CEFOXITIN RESISTANCE

ESCHERICHIA COLI

Abstract

Background: AmpC beta-lactamases are capable to hydrolyse all beta-lactam antibiotics except cefepime and carbapenems. Herbal medicines have been important sources of products for the developing countries in treating common infectious diseases and overcome the problems of resistance and side effects of the currently available antimicrobial agents.Materials and Methods: Total 410 non repetitive clinical E. coli strains recovered during 7 month, were screened for AmpC production by disc diffusion test using cefoxitin (30 mg) discs and confirmed by combined disc diffusion test using phenyl boronic acid and the MIC and MBC of ALLIM SATIVUM (A. sativum) alcoholic extract against AmpC positive E. coli isolates were determined.Results: A total of 107 of 410 isolates (26%) were cefoxitin resistant and 13 (3.1%) isolates harboured AmpC enzymes. A. sativum alcoholic extract were effective against AmpC producing E. coli isolates.Conclusion: There is need for a correct and reliable phenotypic test to identify AmpC beta LACTAMASES and to discriminate between AmpC and ESBL producers and also these bioactive plants may help alleviate the problem of drug resistance.

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APA: Copy

SHAYAN, SARA, BOKAEIAN, MOHAMMAD, SHAHRAKI, SHAHRAM, & SAEIDI, SAEIDE. (2014). PREVALENCE OF AMPC AND ESBL PRODUCING E. COLI AND ANTIBACTERIAL EFFECT OF ALLIM SATIVUM ON CLINICAL ISOLATES COLLECTED FROM ZAHEDAN HOSPITALS. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), 16(4), 6-10. SID. https://sid.ir/paper/661547/en

Vancouver: Copy

SHAYAN SARA, BOKAEIAN MOHAMMAD, SHAHRAKI SHAHRAM, SAEIDI SAEIDE. PREVALENCE OF AMPC AND ESBL PRODUCING E. COLI AND ANTIBACTERIAL EFFECT OF ALLIM SATIVUM ON CLINICAL ISOLATES COLLECTED FROM ZAHEDAN HOSPITALS. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH)[Internet]. 2014;16(4):6-10. Available from: https://sid.ir/paper/661547/en

IEEE: Copy

SARA SHAYAN, MOHAMMAD BOKAEIAN, SHAHRAM SHAHRAKI, and SAEIDE SAEIDI, “PREVALENCE OF AMPC AND ESBL PRODUCING E. COLI AND ANTIBACTERIAL EFFECT OF ALLIM SATIVUM ON CLINICAL ISOLATES COLLECTED FROM ZAHEDAN HOSPITALS,” ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), vol. 16, no. 4, pp. 6–10, 2014, [Online]. Available: https://sid.ir/paper/661547/en

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