SHORT COMMUNICATION: A SURVEY ON THE FREQUENCY OF HLA-B27 IN PATIENTS ENGAGED WITH SERONEGATIVE SPONDYLOARTHROPATHIES IN KASHAN, IRAN

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ESALATMANESH KAMAL; TAGHADOSI MOHSEN; ARJ ABAS

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Journal: Zahedan Journal of Research in Medical Sciences Year:2015 | Volume:17 | Issue:6 Page(s): 1-3

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Title

SHORT COMMUNICATION: A SURVEY ON THE FREQUENCY OF HLA-B27 IN PATIENTS ENGAGED WITH SERONEGATIVE SPONDYLOARTHROPATHIES IN KASHAN, IRAN

Author(s)

ESALATMANESH KAMAL | TAGHADOSI MOHSEN | ARJ ABAS | Issue Writer Certificate

Keywords

SERONEGATIVE

SPONDYLOARTHROPATHIES

HLA-B27

Abstract

Background: SERONEGATIVE SPONDYLOARTHROPATHIES (SNSAs) are referred to a group of diseases with same clinical and genetic features.Objectives: Due to lack of data about HLA-B27 prevalence in patient with SNSA in Kashan this study was conducted to determine the status of HLA-B27 in these patients.Patients and Methods: This cross sectional study was conducted on 294 patients suffered from SNSA. Presence or absence of HLA-B27 was checked by serological method using Greener kit. Results were analyzed with SPSS-16 software using t-test and χ2 test.Results: Of all 26.5% of subjects were HLA-B27 positive. HLA-B27 was significantly more frequent in male patients (34.1% vs. 16.5%, P<0.001). Prevalence of HLA-B27 was 69% in ankylosing spondylitis, 31.5% in psoriatic arthritis, 18.2% in entropathic arthropathy, 17.9% in undifferentiated SPONDYLOARTHROPATHIES, 16.1% in reactive arthritis and 12.5% in juvenile rheumatoid arthritis (P<0.001).Conclusions: HLA-B27 has highest prevalence in ankylosing spondylitis and least prevalence in juvenile rheumatoid arthritis. HLA-B27 prevalence was in relation with gender, type of disease, family history, peripheral, and axial joints engagement.

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APA: Copy

ESALATMANESH, KAMAL, TAGHADOSI, MOHSEN, & ARJ, ABAS. (2015). SHORT COMMUNICATION: A SURVEY ON THE FREQUENCY OF HLA-B27 IN PATIENTS ENGAGED WITH SERONEGATIVE SPONDYLOARTHROPATHIES IN KASHAN, IRAN. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), 17(6), 1-3. SID. https://sid.ir/paper/666073/en

Vancouver: Copy

ESALATMANESH KAMAL, TAGHADOSI MOHSEN, ARJ ABAS. SHORT COMMUNICATION: A SURVEY ON THE FREQUENCY OF HLA-B27 IN PATIENTS ENGAGED WITH SERONEGATIVE SPONDYLOARTHROPATHIES IN KASHAN, IRAN. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH)[Internet]. 2015;17(6):1-3. Available from: https://sid.ir/paper/666073/en

IEEE: Copy

KAMAL ESALATMANESH, MOHSEN TAGHADOSI, and ABAS ARJ, “SHORT COMMUNICATION: A SURVEY ON THE FREQUENCY OF HLA-B27 IN PATIENTS ENGAGED WITH SERONEGATIVE SPONDYLOARTHROPATHIES IN KASHAN, IRAN,” ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), vol. 17, no. 6, pp. 1–3, 2015, [Online]. Available: https://sid.ir/paper/666073/en

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