EPIDERMAL HYDRATION AND SKIN SURFACE LIPIDS IN PATIENTS WITH LONG-TERM COMPLICATIONS OF SULFUR MUSTARD POISONING

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LAYEGH POURAN; MALEKI MASOUD; MOUSAVI SEYED REZA; YOUSEFZADEH HADIS; MOMENZADEH AKRAM; GOLMOHAMMADZADEH SHIVA; BALALI MOOD MAHDI

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Journal: JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS) Year:2015 | Volume:20 | Issue:7 Page(s): 640-645

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Title

EPIDERMAL HYDRATION AND SKIN SURFACE LIPIDS IN PATIENTS WITH LONG-TERM COMPLICATIONS OF SULFUR MUSTARD POISONING

Author(s)

Keywords

EPIDERMAL HYDRATION

SKIN LIPID

SULFUR MUSTARD

XEROSIS

Abstract

Background: Despite almost the three decades passed since the chemical attacks of Iraqi’s army against the Iranian troops, some veterans are still suffering from long-term complications of SULFUR MUSTARD (SM) poisoning, including certain skin complaints specially dryness, burning, and pruritus. We thus aimed to evaluate the skin’s water and lipid content in patients with a disability of >25% due to complications of SM poisoning and compare them with a matched control group.Materials and Methods: Sixty-nine male participants were included in this study; 43 SM-exposed patients, and 26 normal controls from their close relatives. The water and lipid content was measured in four different locations: Extensor and flexor sides of forearms and lateral and medial sides of legs by the Corneometer CM 820/Sebumeter SM 810. Collected data was analyzed and P ≤ 0.05 was considered as statistically significant.Results: The mean age of the patients and controls was 49.53 ± 11.34 (ranges: 40-71) and 29.08 ± 8.836 (ranges: 15-49 years), respectively. In the veterans group, the main cutaneous complaint was itching and skin dryness. Cherry angioma, dry skin, and pruritus were significantly more common in the SM-exposed cases than in the controls. (P = 0.01, 0.05, and 0.04, respectively). The moisture and lipid content of all areas were lower in the SM-exposed group, but it was only significant in skin sebum of lateral sides of legs (P = 0.02). Conclusion: Exposure to SM could decrease the function of stratum corneum and lipid production as a barrier, even after several years of its exposure.

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APA: Copy

LAYEGH, POURAN, MALEKI, MASOUD, MOUSAVI, SEYED REZA, YOUSEFZADEH, HADIS, MOMENZADEH, AKRAM, GOLMOHAMMADZADEH, SHIVA, & BALALI MOOD, MAHDI. (2015). EPIDERMAL HYDRATION AND SKIN SURFACE LIPIDS IN PATIENTS WITH LONG-TERM COMPLICATIONS OF SULFUR MUSTARD POISONING. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 20(7), 640-645. SID. https://sid.ir/paper/668062/en

Vancouver: Copy

LAYEGH POURAN, MALEKI MASOUD, MOUSAVI SEYED REZA, YOUSEFZADEH HADIS, MOMENZADEH AKRAM, GOLMOHAMMADZADEH SHIVA, BALALI MOOD MAHDI. EPIDERMAL HYDRATION AND SKIN SURFACE LIPIDS IN PATIENTS WITH LONG-TERM COMPLICATIONS OF SULFUR MUSTARD POISONING. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2015;20(7):640-645. Available from: https://sid.ir/paper/668062/en

IEEE: Copy

POURAN LAYEGH, MASOUD MALEKI, SEYED REZA MOUSAVI, HADIS YOUSEFZADEH, AKRAM MOMENZADEH, SHIVA GOLMOHAMMADZADEH, and MAHDI BALALI MOOD, “EPIDERMAL HYDRATION AND SKIN SURFACE LIPIDS IN PATIENTS WITH LONG-TERM COMPLICATIONS OF SULFUR MUSTARD POISONING,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 20, no. 7, pp. 640–645, 2015, [Online]. Available: https://sid.ir/paper/668062/en

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