Review Article: Topical Sevoﬂ urane: A Novel Treatment for Chronic Pain Caused by Venous Stasis Ulcers

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Aranke Mayank; Pham Cynthia T.; Yilmaz Melis; Wang Jason K .; Orhurhu Vwaire; An Daniel; Cornett Elyse M.; KAYE ALAN DAVID; Ngo Anh L.; IMANI FARNAD; FARAHMAND RAD REZA; Varrassi Giustino; Viswanath Omar; Urits Ivan

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Journal: ANESTHESIOLOGY AND PAIN MEDICINE Year:2021 | Volume:11 | Issue:1 Page(s): 0-0

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Title

Review Article: Topical Sevoﬂ urane: A Novel Treatment for Chronic Pain Caused by Venous Stasis Ulcers

Author(s)

Keywords

Sevoﬂurane

Venous Stasis Ulcer

Pain

Venous Insuﬃciency

Analgesia

Wound Management

Abstract

In the US, an estimated 1-2% of chronic venous insuﬃ ciency (CVI) patients (of 6-7 million nationwide) develop at least one venous stasis ulcer (VSU) during their illness. Of these, approximately 40% develop subsequent ulcers, making VSU prognostically poor. Current management of VSU is costly, with poor prognosis, high recurrence rate, inadequate pain management, and signiﬁ cantly reduced quality of life (QoL). Topical volatile anesthetic agents, such as sevoﬂ urane, oﬀ er improved pain relief and symptom control in patients suﬀ ering from chronic VSU. The immediate impact of topical sevoﬂ urane in reducing pain associated with ulcer bed debridement has several implications in improving the quality of life in patients with CVI induced ulcers and in the prognosis and healing of the ulcers. This review summarizes a topical formulation of a volatile anesthetic and its implications for the management of VSUs.

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APA: Copy

Aranke, Mayank, Pham, Cynthia T., Yilmaz, Melis, Wang, Jason K ., Orhurhu, Vwaire, An, Daniel, Cornett, Elyse M., KAYE, ALAN DAVID, Ngo, Anh L., IMANI, FARNAD, FARAHMAND RAD, REZA, Varrassi, Giustino, & Urits, Ivan. (2021). Review Article: Topical Sevoﬂ urane: A Novel Treatment for Chronic Pain Caused by Venous Stasis Ulcers. ANESTHESIOLOGY AND PAIN MEDICINE, 11(1), 0-0. SID. https://sid.ir/paper/668210/en

Vancouver: Copy

Aranke Mayank, Pham Cynthia T., Yilmaz Melis, Wang Jason K ., Orhurhu Vwaire, An Daniel, Cornett Elyse M., KAYE ALAN DAVID, Ngo Anh L., IMANI FARNAD, FARAHMAND RAD REZA, Varrassi Giustino, Urits Ivan. Review Article: Topical Sevoﬂ urane: A Novel Treatment for Chronic Pain Caused by Venous Stasis Ulcers. ANESTHESIOLOGY AND PAIN MEDICINE[Internet]. 2021;11(1):0-0. Available from: https://sid.ir/paper/668210/en

IEEE: Copy

Mayank Aranke, Cynthia T. Pham, Melis Yilmaz, Jason K . Wang, Vwaire Orhurhu, Daniel An, Elyse M. Cornett, ALAN DAVID KAYE, Anh L. Ngo, FARNAD IMANI, REZA FARAHMAND RAD, Giustino Varrassi, and Ivan Urits, “Review Article: Topical Sevoﬂ urane: A Novel Treatment for Chronic Pain Caused by Venous Stasis Ulcers,” ANESTHESIOLOGY AND PAIN MEDICINE, vol. 11, no. 1, pp. 0–0, 2021, [Online]. Available: https://sid.ir/paper/668210/en

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