The effect of twelve weeks aerobic training with Rose damascena supplementation on expression of Caspase 3 and 9 genes of Soleus muscle in male rats

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GHASED FATEMEH; BASHIRI JABBAR

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Journal Paper

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Journal: Pars Journal of Medical Sciences Year:2019 | Volume:17 | Issue:1 Page(s): 42-51

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Title

The effect of twelve weeks aerobic training with Rose damascena supplementation on expression of Caspase 3 and 9 genes of Soleus muscle in male rats

Author(s)

GHASED FATEMEH | BASHIRI JABBAR | Issue Writer Certificate

Keywords

Aerobic Exercise

CASP3

CASP9

Rose

Abstract

Introduction: Caspases play an important role in the cellular death process and, on the other hand, Rose has protective effects in this area. The purpose of this study was to investigate the effect of Aerobic Exercises with Rose damascena supplementation on the expression of caspase 3 and 9 genes of soleus muscle in male rats. Materials and Methods: In this experimental study, 50 male Wistar, two-month-old rats were randomly divided into five groups (three-month control, six-month control, exercise, Rose damascena, and combined). Aerobic Exercise and Aerobic Exercises + Rose participated in the treadmill on a gradient of 15% for 5 days a week and for 12 weeks, and the Rose damascena and combined groups received 0. 09 grams of Rose + 9 cc saline per kg body weight with gavage, . After intervention Aerobic Exercises and use of Rose damascena, surgical procedures and extraction of specimens were performed in rats. The data were analyzed by ANOVA at a significant level of less than 0. 05. Results: Caspase 3 and 9 genes expression in soleus muscles of Aerobic Exercise and Rose damascena and combaind group (Rose and Aerobic Exercise) was less pronounced than in six-month control group, respectively, so that in 6 month control group the highest expression was observed. Conclusion: According to the results, Aerobic Exercises and Rose damascena maybe can reduce the rate of cell apoptosis by reducing the expression of Caspase 3 and 9 genes, and slow down the muscle weakness.

Cites

Investigating the Effect of Endurance Training and Supplementation of Persia Rosa Extract on Mitochondrial Apoptosis of Myocardium

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APA: Copy

GHASED, FATEMEH, & BASHIRI, JABBAR. (2019). The effect of twelve weeks aerobic training with Rose damascena supplementation on expression of Caspase 3 and 9 genes of Soleus muscle in male rats. PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL), 17(1 ), 42-51. SID. https://sid.ir/paper/668478/en

Vancouver: Copy

GHASED FATEMEH, BASHIRI JABBAR. The effect of twelve weeks aerobic training with Rose damascena supplementation on expression of Caspase 3 and 9 genes of Soleus muscle in male rats. PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL)[Internet]. 2019;17(1 ):42-51. Available from: https://sid.ir/paper/668478/en

IEEE: Copy

FATEMEH GHASED, and JABBAR BASHIRI, “The effect of twelve weeks aerobic training with Rose damascena supplementation on expression of Caspase 3 and 9 genes of Soleus muscle in male rats,” PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL), vol. 17, no. 1 , pp. 42–51, 2019, [Online]. Available: https://sid.ir/paper/668478/en

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