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Information Journal Paper

Title

ENDOTHELIAL DYSFUNCTION STATE IN MIGRAINE HEADACHE AND NEUTRALLY MEDIATED SYNCOPE IN CHILDREN AND YOUNG ADULTS

Pages

  771-776

Abstract

 Background: Recent evidences have supported MIGRAINE HEADACHE and neurally mediated SYNCOPE as the especial types of endotheliopathies. To determine ENDOTHELIAL FUNCTION in patients with MIGRAINE HEADACHE or those with neurally mediated SYNCOPE, the present study was conducted.Materials and Methods: This cross-sectional study was performed on 93 consecutive patients aged 5-20 years in four groups; neurally mediated SYNCOPE, migraine, both neurally mediated SYNCOPE and migraine, and control groups. All subjects were tested for basic biophysical and biochemical features including age, gender, body mass index, systolic, and diastolic blood pressures, INTIMA-MEDIA THICKNESS (IMT) and FLOW-MEDIATED DILATION (FMD), blood hemoglobin, fasting blood glucose, lipid profile, intercellular adhesion molecule (ICAM), vascular cell adhesion molecule (VCAM), and E-selectin.Results: The mean levels of VCAM and ICAM were significantly higher in all groups when compared to control group (P<0.05). FMD was significantly higher in SYNCOPE, migraine, and SYNCOPE and migraine groups than in the control group (P<0.05). Furthermore, mean IMT was significantly lower in migraine and also in SYNCOPE and migraine groups than in SYNCOPE group and control group (P< 0.05). Examining the association between IMT and other baseline parameters showed positive association of IMT with systolic and diastolic blood pressures.Conclusion: Endothelial dysfunction is seen in both MIGRAINE HEADACHE and neurally mediated SYNCOPE.Changes in ENDOTHELIAL FUNCTIONal indices are also dependent on the blood pressure.

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    APA: Copy

    SABRI, MOHAMMAD REZA, DEHGHAN, BAHAR, YAGHINI, OMID, NASIRI, JAFAR, MANSOURIAN, MARJAN, & KHALIFEHSOLTANI, SHIVA. (2015). ENDOTHELIAL DYSFUNCTION STATE IN MIGRAINE HEADACHE AND NEUTRALLY MEDIATED SYNCOPE IN CHILDREN AND YOUNG ADULTS. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 20(8), 771-776. SID. https://sid.ir/paper/669832/en

    Vancouver: Copy

    SABRI MOHAMMAD REZA, DEHGHAN BAHAR, YAGHINI OMID, NASIRI JAFAR, MANSOURIAN MARJAN, KHALIFEHSOLTANI SHIVA. ENDOTHELIAL DYSFUNCTION STATE IN MIGRAINE HEADACHE AND NEUTRALLY MEDIATED SYNCOPE IN CHILDREN AND YOUNG ADULTS. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2015;20(8):771-776. Available from: https://sid.ir/paper/669832/en

    IEEE: Copy

    MOHAMMAD REZA SABRI, BAHAR DEHGHAN, OMID YAGHINI, JAFAR NASIRI, MARJAN MANSOURIAN, and SHIVA KHALIFEHSOLTANI, “ENDOTHELIAL DYSFUNCTION STATE IN MIGRAINE HEADACHE AND NEUTRALLY MEDIATED SYNCOPE IN CHILDREN AND YOUNG ADULTS,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 20, no. 8, pp. 771–776, 2015, [Online]. Available: https://sid.ir/paper/669832/en

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