Clinical Manifestation of Patients Who Died Due to COVID-19; A Retrospective Study from Qom-Iran

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HORMATI AHMAD; FOROGHI GHOMI Seyed Yaser; SOHRABI MASOUDREZA; Jafari Saeede; JABBARI AMIR; AMINNEJAD REZA; AFIFIAN Mahboubeh; RakhshanKhah Elham; AHMADPOUR SAJJAD

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Journal: ARCHIVES OF IRANIAN MEDICINE Year:2020 | Volume:23 | Issue:12 Page(s): 864-869

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Title

Clinical Manifestation of Patients Who Died Due to COVID-19; A Retrospective Study from Qom-Iran

Author(s)

Keywords

Clinical manifestation

COVID-19

Iran

Middle East

Mortality

Abstract

Background: The coronavirus disease 2019 (COVID-19) has become a pandemic health problem worldwide. In this study, we attempted to explain the clinical and laboratories characteristics of non-surviving patients, to identify the probable factors affecting disease progression. Methods: In a retrospective study, we assessed the data from dead adult patients who were hospitalized and laboratory diagnosed with COVID-19 during March 2020. The data were obtained from electronic medical records. Moreover, a checklist including demographic, clinical, laboratorial, imaging, and treatment data was completed for each one of the patients. In case of lack of information, a member of the research team contacted the first-degree relatives via phone. Results: Totally, 50 patients were enrolled in this study. The mean age was 68. 0 ± 14. 1 years. Of them, 29 (58%) patients were male. Notably, the median (IQR) hospitalization time was 4. 0 (2. 7– 6. 2) days and the duration between the first symptoms to death was 10. 0 (5. 0– 14. 5) days. Also, pre-existing morbidity was reported in 42 (84%) patients, and hypertension was the most common one with 28 (54%) patients. Interestingly, body temperature more than 37. 5° C was reported in only 20 (40%) patients. Nevertheless, neutrophilia (≥ 710 9 /L) and lymphopenia (<1. 0 109/L) were observed in 27 (54%) and 29 (58%) patients, respectively. Also, elevated levels of creatinine, lactate dehydrogenase (LDH), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) were common, which may be indicators of aggravation of the patients’ status. Conclusion: Besides age and underlying diseases, elevated creatinine level, neutrophil count, and the inflammatory indices along with the reduced lymphocyte count can be considered as indicators of disease progression. Hence, they should be considered for admission and surveillance of patients.

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APA: Copy

HORMATI, AHMAD, FOROGHI GHOMI, Seyed Yaser, SOHRABI, MASOUDREZA, Jafari, Saeede, JABBARI, AMIR, AMINNEJAD, REZA, AFIFIAN, Mahboubeh, RakhshanKhah, Elham, & AHMADPOUR, SAJJAD. (2020). Clinical Manifestation of Patients Who Died Due to COVID-19; A Retrospective Study from Qom-Iran. ARCHIVES OF IRANIAN MEDICINE, 23(12), 864-869. SID. https://sid.ir/paper/673342/en

Vancouver: Copy

HORMATI AHMAD, FOROGHI GHOMI Seyed Yaser, SOHRABI MASOUDREZA, Jafari Saeede, JABBARI AMIR, AMINNEJAD REZA, AFIFIAN Mahboubeh, RakhshanKhah Elham, AHMADPOUR SAJJAD. Clinical Manifestation of Patients Who Died Due to COVID-19; A Retrospective Study from Qom-Iran. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2020;23(12):864-869. Available from: https://sid.ir/paper/673342/en

IEEE: Copy

AHMAD HORMATI, Seyed Yaser FOROGHI GHOMI, MASOUDREZA SOHRABI, Saeede Jafari, AMIR JABBARI, REZA AMINNEJAD, Mahboubeh AFIFIAN, Elham RakhshanKhah, and SAJJAD AHMADPOUR, “Clinical Manifestation of Patients Who Died Due to COVID-19; A Retrospective Study from Qom-Iran,” ARCHIVES OF IRANIAN MEDICINE, vol. 23, no. 12, pp. 864–869, 2020, [Online]. Available: https://sid.ir/paper/673342/en

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