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Title

PRE-DISCHARGE SCREENING TRANS-CUTANEOUS BILIRUBINOMETRY IN HEALTHY NEWBORNS IN MAHDIEH HOSPITAL, TEHRAN

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Abstract

 Background: Incidence of jaundice is high in newborn infants. Since well appearing newborns are rapidly and routinely discharged from hospital, performing an inexpensive noninvasive pre-discharge screening test for evaluation of jaundice seems to be necessary.Objectives: This study was conducted to compare the accuracy of cutaneous v/s serum BILIRUBIN measurements in this regard.Patients and Methods: This was a prospective cross sectional study conducted in Mahdieh hospital, Tehran. 613 neonates weighing³1,800 g with gestational age of³35 weeks were enrolled. A pre discharge TRANSCUTANEOUS BILIRUBIN test (TcB) was performed in all. Serum samples were taken from neonates with TCB³5 mg/dL in first and>8 mg/dL in second 24 hours. Decision for treatment or recheck of BILIRUBIN level after discharge was made based on serum BILIRUBIN results.Results: Based on the study protocol, among 613 studied neonates, 491 (80%) revealed high TCB, of them 240 (49%) cases showed TBC³5 mg/dL in first and 251 (51 %) in second pre-discharge 24 hours. TCB ranged 3.3-17.1, mean TCB in first 24 hours was 6.9±1 .7 (mode 6) and in second 24 hours 9.1±2.1 (mode 10). Of 491 neonates with high TCB, capillary serum sample was taken as the second step and 398 neonates revealed high total serum BILIRUBIN (TsB) with the same protocol for TCB. 108 (27.1%) neonates showed TsB³5 mg/dL in first and 290 (72.9%) in second 24 hours. According to the study results TCB has a 81% positive predictive value (PPV) in diagnosis of hyperBILIRUBINemia. Correlation coefficient of TCB and TsB in highest rate is equal to 72% (P value<0.001).Conclusions: TCB is an inexpensive, noninvasive and precise pre-discharge screening test for evaluation of hyperBILIRUBINemia, with a high PPV. It is highly recommended to be performed routinely due to high incidence of hyperBILIRUBINemia in neonates.

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    APA: Copy

    AFJEHI, ABOLFAZL, FALLAHI, MINOO, BASIRI, AZITA, & ALLAEE, MASTANEH. (2015). PRE-DISCHARGE SCREENING TRANS-CUTANEOUS BILIRUBINOMETRY IN HEALTHY NEWBORNS IN MAHDIEH HOSPITAL, TEHRAN. IRANIAN JOURNAL OF PEDIATRICS, 25(4), 0-0. SID. https://sid.ir/paper/677673/en

    Vancouver: Copy

    AFJEHI ABOLFAZL, FALLAHI MINOO, BASIRI AZITA, ALLAEE MASTANEH. PRE-DISCHARGE SCREENING TRANS-CUTANEOUS BILIRUBINOMETRY IN HEALTHY NEWBORNS IN MAHDIEH HOSPITAL, TEHRAN. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2015;25(4):0-0. Available from: https://sid.ir/paper/677673/en

    IEEE: Copy

    ABOLFAZL AFJEHI, MINOO FALLAHI, AZITA BASIRI, and MASTANEH ALLAEE, “PRE-DISCHARGE SCREENING TRANS-CUTANEOUS BILIRUBINOMETRY IN HEALTHY NEWBORNS IN MAHDIEH HOSPITAL, TEHRAN,” IRANIAN JOURNAL OF PEDIATRICS, vol. 25, no. 4, pp. 0–0, 2015, [Online]. Available: https://sid.ir/paper/677673/en

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